Prevalence Of Oral Mucosal Alterations In Diabetes Mellitus Type2

NCT03670797 | Completed DMC

• 1 other identifier: Diabetes-Oral Alterations
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

There are severe deficiency of database concerning the oral health status in Egyptian patients with Diabetes type 2. Our aim in the present study is to study the prevalence of oral mucosal alterations in type 2 DM patients and the effect of hyperglycemia on these alterations in controlled and uncontrolled patients to increase their awareness and minimize all the possible risk factors,to achieve a proper management for all oral problems.

Conditions

Oral Disease; Diabetes

Keywords

oral health status; oral findings; oral manifestations; patients with diabetes

Outcome Measures

Primary Outcomes (1)

• Oral mucosal alterations

  Clinical examination according to WHO guidelines by Dichotomous outcome (Yes/No).

  10 min

Secondary Outcomes (2)

• Periodontal condition

  10 min

• Salivary glands function

  10 min

Study Arms (2)

controlled diabetic patients

uncontrolled diabetic patients

Eligibility Criteria

• Age: 25 Years - 90 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A convenience sample of adult patients diagnosed with diabetes type 2 attending at the Endocrine clinic at El Kasr Al-Ainy Cairo University Hospital will be enrolled in the study in a consecutive order.

You may qualify if:

• Adult patients
• Patients \>25years old
• Patients diagnosed with diabetes type 2.
• Egyptian patients.

You may not qualify if:

• females diagnosed with gestational diabetes.
• Patients not physically able to participate in survey or clinical oral examination.
• Patients with other systemic diseases which may cause oral manifestation as liver disorders.
• Patients under immunosuppressive drugs.
• Patients under corticosteriods.
• Patients with organ transplantation.

Sponsors & Collaborators

• Alaa Mahmoud abd El kader: lead
• Cairo University: collaborator

Study Sites (1)

Alaa Mahmoud Abd El Kader

Cairo, 2020, Egypt

Location

Related Publications (2)

• Al-Maweri SA, Ismail NM, Ismail AR, Al-Ghashm A. Prevalence of oral mucosal lesions in patients with type 2 diabetes attending hospital universiti sains malaysia. Malays J Med Sci. 2013 Jul;20(4):39-46.

  PMID: 24043995 RESULT

• Bastos AS, Leite AR, Spin-Neto R, Nassar PO, Massucato EM, Orrico SR. Diabetes mellitus and oral mucosa alterations: prevalence and risk factors. Diabetes Res Clin Pract. 2011 Apr;92(1):100-5. doi: 10.1016/j.diabres.2011.01.011. Epub 2011 Mar 3.

  PMID: 21300417 RESULT

MeSH Terms

Conditions

Mouth Diseases; Diabetes Mellitus; Oral Manifestations

Condition Hierarchy (Ancestors)

Stomatognathic Diseases; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Mariam fakhr

  the Endocrine units at the Kasr Al-Ainy Cairo university hospital.

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: principle investigator, internal resident at oral medicine department

Study Record Dates

• First Submitted: September 12, 2018
• First Posted: September 14, 2018
• Study Start: December 25, 2018
• Primary Completion: July 30, 2019
• Study Completion: August 20, 2019
• Last Updated: January 28, 2020

Record last verified: 2020-01

Locations

EG (1)