Does Salt Intake Improve Mood

NCT03467568 | Unknown

• 1 other identifier: DB-0123-SALT
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Humans display a preference for salt although the reasons remain unclear. The aim was to examine the hypothesis that salt may enhance mood. The study compares the drinking of water with and without electrolytes (either dissolved in water or by capsule). Mood was rated over a period of 155 minutes

Conditions

Mood; Salt Intake

Keywords

Mood Salt

Outcome Measures

Primary Outcomes (1)

• Mood ratings using visual analogue scales

  On a hundred millimetre scale ratings will be made of with the two ends anchored with the words Agreeable/Hostile, Confused/clearheaded; composed/anxious; depressed/elated; confident/unsure; tired/energetic. Each scales produces a score between 0 and 100. When added to create a total mood score the ratings vary between zero and six hundred with a higher score indicating a better mood

  Up to three hours

Secondary Outcomes (2)

• Ratings of thirst

  Up to three hours

• Body weight

  Up to three hours

Study Arms (4)

Sodium chloride / Water

ACTIVE COMPARATOR

The sodium chloride / water arm involves 300mg sodium chloride being consumed in a capsule and on two occasions 150ml of water being drunk

Dietary Supplement: Sodium Chloride; Dietary Supplement: Water

Sodium chloride / no water

ACTIVE COMPARATOR

A capsule containing 300mg of sodium chloride will be consumed but no water will be drunk over the morning

Dietary Supplement: Sodium Chloride; Biological: No water consumed

Placebo / water

ACTIVE COMPARATOR

A capsule containing a placebo will be consumed and on two occasions 150ml of water will be drunk

Other: Placebo capsule; Dietary Supplement: Water

Placebo / no water

PLACEBO COMPARATOR

A capsule containing a placebo will be consumed but no water will be drunk over the morning

Other: Placebo capsule; Biological: No water consumed

Interventions

Sodium Chloride DIETARY_SUPPLEMENT

300mg sodium chloride will be provided in a capsule

Sodium chloride / Water; Sodium chloride / no water

Placebo capsule OTHER

A capsule of identical appearance to that providing salt, but not containing electrolytes, will be consumed

Placebo / no water; Placebo / water

Water DIETARY_SUPPLEMENT

Twice during the morning a drink of 150ml of water will be consumed

Placebo / water; Sodium chloride / Water

No water consumed BIOLOGICAL

No water will be consumed during the monring

Placebo / no water; Sodium chloride / no water

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Swansea University: lead

Study Sites (1)

Psychology, Swansea University

Swansea, Wales, sa2 8pp, United Kingdom

RECRUITING

MeSH Terms

Interventions

Sodium Chloride; Water

Intervention Hierarchy (Ancestors)

Chlorides; Hydrochloric Acid; Chlorine Compounds; Inorganic Chemicals; Sodium Compounds; Hydroxides; Alkalies; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds

Central Study Contacts

David Benton, DSc

CONTACT

++441792295607; d.benton@swansea.ac.uk

Hayley Young, PhD

CONTACT

++441792295908; h.a.young@swansea.a.cuk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Salt / placebo will be consumed by capsule under a double blind procedure
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: The study has four arms. Salt alone; salt plus water; placebo alone, placebo plus water

Study Record Dates

• First Submitted: February 16, 2018
• First Posted: March 16, 2018
• Study Start: January 1, 2017
• Primary Completion: April 1, 2018
• Study Completion: April 1, 2018
• Last Updated: March 16, 2018

Record last verified: 2018-03

Data Sharing

• IPD Sharing: Will not share

Locations

GB (1)