NCT03461237

Brief Summary

  1. 1.To Compare overall rates of second hip fractures in both genders,
  2. 2.To determine the effect of hip fracture on proximal femoral volumetric bone mineral density (vBMD), bone structure and muscle by quantitative computed tomography(QCT),
  3. 3.To evaluate the contribution of QCT-image analysis to the prediction of the second hip fracture risk.
  4. 4.To identify the differences between femoral neck fracture and trochanter fracture following hip fracture

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,000

participants targeted

Target at P75+ for all trials

Timeline
3mo left

Started May 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
May 2017Nov 2026

Study Start

First participant enrolled

May 1, 2017

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

March 5, 2018

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 9, 2018

Completed
8.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2026

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2026

Expected
Last Updated

August 17, 2025

Status Verified

February 1, 2025

Enrollment Period

9 years

First QC Date

March 5, 2018

Last Update Submit

August 13, 2025

Conditions

Keywords

Second Hip FractureQuantitative Computed TomographyBone structureMuscle

Outcome Measures

Primary Outcomes (2)

  • Hip re-fracture

    The incidence and location of second hip fracture

    3 years

  • all cause death

    all cause death

    2 year

Eligibility Criteria

Age50 Years - 95 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

This is a cohort-based study. 3000 participants (including 1800 females and 1200 males) who (\>47 years old) have recently suffered single hip fracture will be recruited to the study.

You may qualify if:

  • a:Osteoporotic patients b:Osteoporotic hip fracture patients (femoral neck fracture and femoral trochanteric fracture) c: Be willing to and be able to join in the study and sighed the informed consent

You may not qualify if:

  • a:Under 47years old b:Non-surgical repair of hip fracture c:Pathologic fracture d:Violence-related trauma e:Bilateral hip implants or have hip replacement on the non-fractured side

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Beijing ji shui tan hospital

Beijing, Beijing Municipality, 100035, China

RECRUITING

Related Publications (1)

  • Ma Y, Ge Y, Guo Z, Su Y, Wang C, Wang Q, Wang L, Cheng X, Yang M, Yan D. Hip structural analysis parameters are not associated with the risk of postmenopausal female second hip fracture: a retrospective study. BMC Musculoskelet Disord. 2025 Mar 10;26(1):233. doi: 10.1186/s12891-025-08368-7.

MeSH Terms

Conditions

Hip FracturesOsteoporosis

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg InjuriesBone Diseases, MetabolicBone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Xiaoguang Cheng, MD

    department of radiology, Beijing Jishuitan Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Xiaoguang Cheng, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chairman, Department of Radiology

Study Record Dates

First Submitted

March 5, 2018

First Posted

March 9, 2018

Study Start

May 1, 2017

Primary Completion

May 1, 2026

Study Completion (Estimated)

November 1, 2026

Last Updated

August 17, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will not share

Locations