Outcome After TIPS

NCT03459378 | Completed

• 1 other identifier: Retro-TIPS
• Study Type: observational
• Target: 158
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial is a retrospective single-centre study. Research data will be acquired via patient histories stored in the hospital data system. Data of patients who received a Transjugular Intrahepatic Portosystemic Shunt (TIPS) at the University Hospital Graz between 1.1.2004 and 31.12.2017 will be included into the study. The aim is to investigate the outcome (transplantation free survival, time to (re)occurrence of ascites, occurrence of hepatic encephalopathy) of patients with portal hypertension after TIPS.

Conditions

Hypertension, Portal; Liver Cirrhosis; Variceal Hemorrhage; Ascites Hepatic

Outcome Measures

Primary Outcomes (1)

• transplantation free survival

  Survival without liver Transplantation in days

  from date of TIPS until the event, up to 4 years

Secondary Outcomes (2)

• occurrence of hepatic encephalopathy

  from date of TIPS until the event, up to 4 years

• occurrence of ascites

  from date of TIPS until the event, up to 4 years

Interventions

no intervention - retrospective analyses OTHER

retrospective data examination, there are no study related interventions

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients at the age of 18-90 years who received a Transjugular Intrahepatic Portosystemic Shunt at the University Hospital of Graz/Austria between 1.1.2004 and 31.12.2017

You may qualify if:

• every person at the age of 18-90 years who received a Transjugular Intrahepatic Portosystemic Shunt at the University Hospital of Graz/Austria between 1.1.2004 and 31.12.2017

You may not qualify if:

• age under 18

Sponsors & Collaborators

• Medical University of Graz: lead

Study Sites (1)

Medical University of Graz

Graz, 8010, Austria

Location

Related Publications (1)

• Furschuss L, Rainer F, Effenberger M, Niederreiter M, Portugaller RH, Horvath A, Fickert P, Stadlbauer V. A novel score predicts mortality after transjugular intrahepatic portosystemic shunt: MOTS - Modified TIPS Score. Liver Int. 2022 Aug;42(8):1849-1860. doi: 10.1111/liv.15236. Epub 2022 Apr 1.

  PMID: 35261130 DERIVED

MeSH Terms

Conditions

Hypertension, Portal; Liver Cirrhosis

Condition Hierarchy (Ancestors)

Liver Diseases; Digestive System Diseases; Fibrosis; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 26, 2018
• First Posted: March 8, 2018
• Study Start: March 23, 2018
• Primary Completion: March 1, 2019
• Study Completion: May 14, 2020
• Last Updated: May 15, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

AU (1)