Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

8.6%

3 terminated out of 35 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

9%

3 trials in Phase 3/4

Results Transparency

42%

5 of 12 completed with results

Key Signals

5 with results80% success

Data Visualizations

Phase Distribution

28Total
Not Applicable (16)
P 2 (9)
P 3 (1)
P 4 (2)

Trial Status

Completed12
Unknown10
Recruiting4
Not Yet Recruiting3
Terminated3
Active Not Recruiting2

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 12 completed trials

Clinical Trials (35)

Showing 20 of 20 trials
NCT07462091Not ApplicableRecruiting

Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection

NCT07461545Not ApplicableRecruiting

Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS

NCT07461532Not ApplicableRecruiting

Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD

NCT06437964Not ApplicableActive Not Recruiting

Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding

NCT05282121Phase 2Terminated

A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

NCT05161481Phase 2TerminatedPrimary

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

NCT06082843Phase 2TerminatedPrimary

A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Belly

NCT04315571Not ApplicableActive Not RecruitingPrimary

Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents

NCT04645550Phase 4Completed

Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy(ESAWAAPT)

NCT04720456Phase 2RecruitingPrimary

SHAPE of Portal Hypertension in Children

NCT06696248Phase 2Not Yet RecruitingPrimary

Carvedilol and Alverine in Portal Hypertension

NCT04044248Completed

TIPS Plus Transvenous Obliteration for Gastric Varices

NCT06473493Phase 2Not Yet RecruitingPrimary

The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension

NCT06470386Phase 2Not Yet RecruitingPrimary

The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosis

NCT05304455Not ApplicableCompleted

Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal Disconnection

NCT04668664Completed

Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements

NCT05041452UnknownPrimary

Multiparametric Cardio-hepatic MRI in Patients With Noncirrhotic Portal Hypertension

NCT03713606UnknownPrimary

Serum Biomarkers for Portal Hypertension in Cirrhosis (Pan-CHESS1802)

NCT03175731Phase 4Completed

PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors)

NCT02462967Phase 2CompletedPrimary

Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosis

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