NCT03457428

Brief Summary

Earlier studies suggest that acoustical analysis of snoring sounds can identify obstructive sleep apnea (OSA). The goal of the current study is to refine and validate algorithms for OSA diagnosis.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
83

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2017

Geographic Reach
1 country

4 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 31, 2017

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 19, 2018

Completed
16 days until next milestone

First Posted

Study publicly available on registry

March 7, 2018

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

February 26, 2019

Status Verified

February 1, 2019

Enrollment Period

1.1 years

First QC Date

February 19, 2018

Last Update Submit

February 22, 2019

Conditions

Keywords

obstructive sleep apneahome sleep testing

Outcome Measures

Primary Outcomes (1)

  • Level of agreement between Sleep Breathing Index Score obtained from analysis by the proprietary algorith, and the Apnea-Hypopnea Index (AHI) as obtained by HST, with a cut-off of 15

    Level of agreement between the Sleep Breathing Index Score obtained from analysis by the proprietary algorithm, and the Apnea-Hypopnea Index (AHI) as obtained by HST, with a cut-off of 15.

    immediate

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population includes patients who are referred for polysomnography because of possible obstructive sleep apnea (OSA).

You may qualify if:

  • referred for polysomnography (PSG) because of possible obstructive sleep apnea (OSA)
  • owns/possesses a smartphone for use during the study. Must be:
  • Android models running Android OS Samsung Galaxy 5 or later
  • iPhone models running iOS 6 or later

You may not qualify if:

  • previous PSG or home sleep testing (HST) confirmation of OSA
  • prior surgery for snoring or OSA
  • medical contraindication of HST, as applicable
  • congnitive impairment that might interfere with obtaining informed consent, or completing Clinical Questionnaire

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Peninsula Sleep Center

Burlingame, California, 94010, United States

Location

Santa Monica Clinical Trials

Santa Monica, California, 90404, United States

Location

Blue Sleep

New York, New York, 10006, United States

Location

Sounds Sleep Health

Kirkland, Washington, 98034, United States

Location

Related Publications (2)

  • Karunajeewa AS, Abeyratne UR, Hukins C. Multi-feature snore sound analysis in obstructive sleep apnea-hypopnea syndrome. Physiol Meas. 2011 Jan;32(1):83-97. doi: 10.1088/0967-3334/32/1/006. Epub 2010 Nov 30.

    PMID: 21119221BACKGROUND
  • Abeyratne UR, de Silva S, Hukins C, Duce B. Obstructive sleep apnea screening by integrating snore feature classes. Physiol Meas. 2013 Feb;34(2):99-121. doi: 10.1088/0967-3334/34/2/99. Epub 2013 Jan 23.

    PMID: 23343563BACKGROUND

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Jon Freudman, MD

    Resonea, Inc

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 19, 2018

First Posted

March 7, 2018

Study Start

October 31, 2017

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

February 26, 2019

Record last verified: 2019-02

Locations