NCT03454477

Brief Summary

Comparison of endoscopic thyroidectomy, robotic thyroidectomy and conventional open surgery, the safety of the operation, the timing of the operation and the complications.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2018

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

February 7, 2018

Completed
27 days until next milestone

First Posted

Study publicly available on registry

March 6, 2018

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
Last Updated

September 18, 2018

Status Verified

September 1, 2018

Enrollment Period

8 months

First QC Date

February 7, 2018

Last Update Submit

September 17, 2018

Conditions

Keywords

EndoscopyRoboticsThyroidectomyPapillary Thyroid Carcinoma

Outcome Measures

Primary Outcomes (2)

  • operation time

    Assess the operation time

    The first day after surgery

  • recurrent laryngeal nerve palsy

    the number of recurrent laryngeal nerve palsy

    2 months post operation

Secondary Outcomes (2)

  • thyroid volume

    The day before the operation

  • cosmetic effect

    2 months post operation

Study Arms (3)

conventional open surgery

EXPERIMENTAL

Patients who met the inclusion criteria were selected for a conventional open surgery procedure for a conventional neck incision for thyroid surgery.

Procedure: conventional open surgery

endoscopic thyroidectomy

EXPERIMENTAL

Patients who met the inclusion criteria were selected to undergo thyroid surgery via endoscopic thyroidectomy

Procedure: endoscopic thyroidectomy

robotic thyroidectomy

EXPERIMENTAL

Patients who met the inclusion criteria chose the Da Vinci robot for thyroid surgery.

Device: robotic thyroidectomy

Interventions

conventional open surgery

conventional open surgery

endoscopic thyroidectomy

endoscopic thyroidectomy

robotic thyroidectomy

robotic thyroidectomy

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Thyroid papillary carcinoma.
  • The tumor diameter is less than or equal to 1cm.
  • The lymph nodes are limited to the VI level.
  • Voluntary choice of endoscopy or robotic surgery.

You may not qualify if:

  • Patients without beauty needs.
  • There is lateral neck or mediastinal lymph node metastasis.
  • The tumor invades the nerve and surrounding organs.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wen-xin ZHAO

Fuzhou, Fujian, 350001, China

RECRUITING

MeSH Terms

Conditions

Thyroid Cancer, Papillary

Condition Hierarchy (Ancestors)

Adenocarcinoma, PapillaryAdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsThyroid NeoplasmsEndocrine Gland NeoplasmsNeoplasms by SiteHead and Neck NeoplasmsEndocrine System DiseasesThyroid Diseases

Central Study Contacts

wenxin zhao, md

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
clinical professor

Study Record Dates

First Submitted

February 7, 2018

First Posted

March 6, 2018

Study Start

February 1, 2018

Primary Completion

October 1, 2018

Study Completion

October 1, 2018

Last Updated

September 18, 2018

Record last verified: 2018-09

Locations