NCT01338597

Brief Summary

The purpose of this study is to investigate whether reduced subcutaneous dissection area could offer patients more clinical benefits.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2011

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

April 11, 2011

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 19, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
Last Updated

April 19, 2011

Status Verified

April 1, 2011

Enrollment Period

8 months

First QC Date

April 11, 2011

Last Update Submit

April 18, 2011

Conditions

Keywords

thyroidectomyinvasiveness

Outcome Measures

Primary Outcomes (1)

  • post-operative pain

    24hs after operation, post-operative pain is evaluated by VAS(visual analoge scale)

    24h post-operation

Secondary Outcomes (1)

  • number of patients with adverse effect

    within 3 months after surgery

Study Arms (2)

standard

EXPERIMENTAL

3 trocars are needed. two in the circumareolar region and one in the parasternal region. the dissection area begins from the trocar site and extends to the neck.

Procedure: endoscopic thyroidectomy

limited dissection

EXPERIMENTAL

the dissection is reduced by creating a long tunnel from the trocar site and the dissection area confined in the upper chest wall and in the neck.

Procedure: endoscopic thyroidectomy

Interventions

endoscopic thyroidectomy via the breast approach. the difference between two arms is in the subcutaneous dissection area.

Also known as: limited flap dissection endoscopic thyroidectomy
limited dissectionstandard

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • thyroid nodule diagnosed by ultrasound
  • willing to undergo endoscopic thyroidectomy

You may not qualify if:

  • conversion to open surgery
  • unwilling to join the research

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of General Surgery, Changzheng Hospital

Shanghai, Shanghai Municipality, 200003, China

Location

Related Publications (1)

  • Wang M, Zhang T, Mao Z, Dong F, Li J, Lu A, Hu W, Zang L, Jiang Y, Zheng M. Effect of endoscopic thyroidectomy via anterior chest wall approach on treatment of benign thyroid tumors. J Laparoendosc Adv Surg Tech A. 2009 Apr;19(2):149-52. doi: 10.1089/lap.2008.0296.

MeSH Terms

Conditions

Thyroid Neoplasms

Condition Hierarchy (Ancestors)

Endocrine Gland NeoplasmsNeoplasms by SiteNeoplasmsHead and Neck NeoplasmsEndocrine System DiseasesThyroid Diseases

Study Officials

  • ming qiu, MD

    Changzheng Hospital

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

April 11, 2011

First Posted

April 19, 2011

Study Start

April 1, 2011

Primary Completion

December 1, 2011

Study Completion

June 1, 2012

Last Updated

April 19, 2011

Record last verified: 2011-04

Locations