Impact of Another Person's Presence on Brain and Behavioral Performance

NCT03453216 | Terminated

• 1 other identifier: 2016-A01477-44
• Study Type: interventional
• Target: 112
• Locations: 1 country
• Sites: 1

Brief Summary

In a recent study, investigators provided the first neuroscientific data on social facilitation. This neuroimaging study, performed in the macaque monkey, shows a marked improvement in performance in a simple task when a congener is present compared to when the animal performs the task alone. This social facilitation is accompanied by a significant increase in brain activity within the fronto-parietal network of attention. No variation in activity, however, is observed in the cerebral network of motivation. These results argue in favor of the implication of attentional processes in the phenomenon of social facilitation. The challenge now is to determine whether social facilitation is always based on the attention network (whatever the task) or, alternatively, whether it increases activity in any cerebral circuit involved depending on the task performed and the population studied. This hypothesis, which the investigators have named the "multi-mediator model of social facilitation", has the advantage of reconciling the attentional and motivational theories of social facilitation, which are not mutually exclusive. This hypothesis also provides an explanation for the pervasiveness (across species and different ages for humans) of social facilitation. The main objective of SOFEE is to gather neuroscientific evidence to support the multi-facilitator model of social facilitation.

Conditions

Behavior and Behavior Mechanisms

Outcome Measures

Primary Outcomes (2)

• Behavioral performance evaluation

  percentage of correct answers and reaction time when performing cognitive number and rhyme comparison tasks in the presence or absence of a familiar peer

  an average of 5 years

• identification through Functional Magnetic Resonance Imaging (fMRI ) of brain activity related to the presence of others

  Comparison of activity in the three populations tested (children, adolescents, adults)

  an average of 5 years

Secondary Outcomes (1)

• Determination of individual characteristics

  an average of 5 years

Study Arms (1)

Behavioral test and fMRI

EXPERIMENTAL

Neuropsychological tests and training in behavioral tasks and a Functional Magnetic Resonance Imaging (fMRI) exam

Behavioral: neuropsychological tests

Interventions

neuropsychological tests BEHAVIORAL

Part 1: to determine the cognitive capacity, the subjects undergo different neuropsychological tests To determine individual characteristics children, adolescents and adults complete self-assessment questionnaires . Adults spend a semi-directive interview. Part 2: while the subject 1 (S1) is installed in the MRI, he perform behavioral tasks with the subject 2 (S2) (familiar peer of the same age ± 2 years) installed in an adjacent room, alternating periods when S1 is observed by S2 (condition "Social") and periods when S1 is not observed by S2 (condition "Alone").

Also known as: Functional Magnetic Resonance Imaging (fMRI) exam

Behavioral test and fMRI

Eligibility Criteria

• Age: 8 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Girl or boy aged ≥ 8 years and ≤ 12 years old for children,
• Girl or boy aged ≥ 13 years and ≤ 19 years old for teenagers,
• Woman or man age ≥ 20 years and ≤ 35 years old for young adults,
• French mother tongue,
• With the right to a social security scheme or similar,
• With informed consent form signed by the legal representatives and the subject, for minors,
• Has signed the informed consent form, for adults.

You may not qualify if:

• Known acquired neurological disorders, including epilepsy,
• Known psychiatric disorders,
• Complications at birth requiring admission to neonatal intensive care unit,
• Ongoing treatment with drugs affecting the central nervous system,
• Significant hearing impairment,
• Uncorrected visual inadequacy,
• Left manual preference,
• Contraindications to the MRI examination (people using a pacemaker or an insulin pump, people wearing a metal prosthesis or an intracerebral clip as well as claustrophobic subjects),
• Refusal of the subject or parents of the subject to be informed of any anomalies detected on the MRI,
• Protected persons other than children

Sponsors & Collaborators

• Hôpital le Vinatier: lead

Study Sites (1)

CH Le Vinatier

Bron, Auvergne-Rhône-Alpes, 69678, France

Location

MeSH Terms

Conditions

Behavior

Interventions

Neuropsychological Tests

Intervention Hierarchy (Ancestors)

Psychological Tests; Behavioral Disciplines and Activities

Study Officials

• POISSON ALICE, MD

  CH LE VINATIER

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 14, 2018
• First Posted: March 5, 2018
• Study Start: July 1, 2019
• Primary Completion: October 5, 2022
• Study Completion: October 5, 2022
• Last Updated: August 5, 2025

Record last verified: 2025-07

Locations

FR (1)