Increasing the Uptake of Influenza and Pneumococcal Vaccines Among High-Risk Adult Patients Through GP Clinics

NCT03445117 | Completed

• 1 other identifier: DSRB 2017/00441
• Study Type: interventional
• Target: 8,837
• Locations: 1 country
• Sites: 2

Brief Summary

Pneumonia and influenza are among the top causes of hospitalisation and death in the elderly. While vaccinations are recommended against these diseases, a large proportion of elderly in the community remain unvaccinated, with approximately only 10% vaccinated for either disease. In this study, the investigators aim to implement an intervention package within GP clinics to increase influenza and pneumococcal vaccination rates, especially among elderly patients with chronic diseases.

Conditions

Immunization Programs

Keywords

Influenza Vaccines; Pneumococcal Vaccines; Primary Health Care; Health Communication; Cross-Over Studies; Randomized Controlled Trial

Outcome Measures

Primary Outcomes (2)

• Difference in influenza vaccination uptake rate for clinics between intervention and non-intervention periods

  The proportion of all eligible patients arriving at each clinic who receive influenza vaccine during the intervention period compared to the non-intervention period for each clinic.

  8 months (post-study completion)

• Difference in pneumococcal vaccination uptake rate for clinics between intervention and non-intervention periods

  The proportion of all eligible patients arriving at each clinic who receive pneumococcal vaccine during the intervention period compared to the non-intervention period for each clinic.

  8 months (post-study completion)

Study Arms (2)

Intervention

EXPERIMENTAL

Clinics assigned to the intervention arm will receive an educational intervention. This comprises posters on vaccination to be put up in the clinic, as well as a flyer which will be handed out by the clinic assistants to all patients 65 years and above, at the point of registration. The poster and flyer content will provide simple messaging to encourage patients to receive influenza and pneumococcal vaccinations and inform them of available healthcare subsidies.

Other: Educational intervention

Control

NO INTERVENTION

Clinics assigned to control arm will run as per their normal operations and not have the interventions implemented.

Interventions

Educational intervention OTHER

a) The educational intervention comprises putting up posters on vaccination in the clinic, as well as provision of a specially designed flyer to the clinic, which will be handed out by the clinic assistants to all patients 65 years and above, at the point of registration. The poster and flyer content will provide simple messaging to encourage patients to receive influenza and pneumococcal vaccinations and inform them of available healthcare subsidies. b) Reminders to physicians: The flyers will also serve as physical prompts to physicians to encourage vaccination for their patients. Doctors and clinic staff will also be updated on the study protocol and the recommended adult vaccination schedule before commencement of the study.

Intervention

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Patients seen at GP clinics involved in our study AND
• Aged 65 years and above, with or without chronic disease

You may not qualify if:

• Patients not seen at GP clinics involved in our study
• Patients aged below 65 years old

Sponsors & Collaborators

• Tan Tock Seng Hospital: lead
• Frontier Healthcare Group: collaborator
• OneCare Medical Group: collaborator

Study Sites (2)

Frontier Healthcare Group

Singapore, 400305, Singapore

Location

OneCare Medical Group

Singapore, 609966, Singapore

Location

Related Publications (1)

• Ho HJ, Tan YR, Cook AR, Koh G, Tham TY, Anwar E, Hui Chiang GS, Lwin MO, Chen MI. Increasing Influenza and Pneumococcal Vaccination Uptake in Seniors Using Point-of-Care Informational Interventions in Primary Care in Singapore: A Pragmatic, Cluster-Randomized Crossover Trial. Am J Public Health. 2019 Dec;109(12):1776-1783. doi: 10.2105/AJPH.2019.305328. Epub 2019 Oct 17.

  PMID: 31622142 DERIVED

MeSH Terms

Conditions

Influenza, Human

Interventions

Early Intervention, Educational

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Child Health Services; Community Health Services; Health Services; Health Care Facilities Workforce and Services; Preventive Health Services

Study Officials

• Dr Hanley Ho

  Tan Tock Seng Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: two-arm cluster randomised crossover trial

Study Record Dates

• First Submitted: January 28, 2018
• First Posted: February 26, 2018
• Study Start: November 1, 2017
• Primary Completion: July 31, 2018
• Study Completion: July 31, 2018
• Last Updated: July 5, 2019

Record last verified: 2019-06

Data Sharing

• IPD Sharing: Will not share

Locations

SG (2)