NCT03437655

Brief Summary

The aim of this study is through a randomized clinical trial, double blind, splithmouth, evaluate the success rate (retation rate and dental sensibility) of temporary direct restorations in vital teeth. The composition of the temporary direct restoration (based on Zinc-Oxide with Eugenol; and mineral trioxide aggregate). Data will be collected, tabulated and submitted to statistical analysis.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 11, 2018

Completed
8 days until next milestone

First Posted

Study publicly available on registry

February 19, 2018

Completed
29 days until next milestone

Study Start

First participant enrolled

March 20, 2018

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2018

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 30, 2018

Completed
Last Updated

March 7, 2018

Status Verified

March 1, 2018

Enrollment Period

1 month

First QC Date

February 11, 2018

Last Update Submit

March 6, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Success rate (retention rate and absence of sensibility) of temporary direct restoration with diferents temporary materials with a 15 days of follow up

    15 days

Study Arms (2)

Zinc oxide and eugenol

ACTIVE COMPARATOR

Temporary direct restoration with zinc oxide and eugenol.

Procedure: Carie removalProcedure: Relative isolationProcedure: Manipulation of the temporary material based on Zinc Oxide and EugenolProcedure: Material insertion on the cavityProcedure: Finishing the temporary direct restoration

Mineral trioxide aggregate

ACTIVE COMPARATOR

Temporary direct restoration with Mineral trioxide aggregate.

Procedure: Carie removalProcedure: Relative isolationProcedure: Manipulation of the temporary material based on Mineral trioxide aggregateProcedure: Material insertion on the cavityProcedure: Finishing the temporary direct restoration

Interventions

Carie removalPROCEDURE

Carie removal with a low speed handpiece

Mineral trioxide aggregateZinc oxide and eugenol

Relative isolation with cotton and gauze.

Mineral trioxide aggregateZinc oxide and eugenol

Manipulation of the temporary material based on Zinc Oxide and Eugenol according to the manufacturer's recommendations

Zinc oxide and eugenol

Manipulation of the temporary material based on Mineral trioxide aggregate according to the manufacturer's recommendations

Mineral trioxide aggregate

Material insertion on the cavity according to the manufacturer's recommendations

Mineral trioxide aggregateZinc oxide and eugenol

Excess cement removal; Occlusal Adjustment; Finishing and polishing.

Mineral trioxide aggregateZinc oxide and eugenol

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy volunteers; both genres; presence of at least two teeth with indication of direct restoration; good oral hygiene.

You may not qualify if:

  • Dentures or orthodontics; presence of periodontal disease and,or parafunctional habits; systemic disease and, or severe psychological; constant use of analgesic and, or anti-inflammatory or allergic response to dental products.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Federal University of Uberlandia

Uberlândia, Minas Gerais, 381440617, Brazil

Location

Related Publications (9)

  • Al Jabbari YS, Al-Rasheed A, Smith JW, Iacopino AM. An indirect technique for assuring simplicity and marginal integrity of provisional restorations during full mouth rehabilitation. Saudi Dent J. 2013 Jan;25(1):39-42. doi: 10.1016/j.sdentj.2012.10.003. Epub 2012 Nov 10.

    PMID: 23960554BACKGROUND
  • Arora SJ, Arora A, Upadhyaya V, Jain S. Comparative evaluation of marginal leakage of provisional crowns cemented with different temporary luting cements: In vitro study. J Indian Prosthodont Soc. 2016 Jan-Mar;16(1):42-8. doi: 10.4103/0972-4052.164911.

    PMID: 27134427BACKGROUND
  • Fonseca RB, Martins LR, Quagliatto PS, Soares CJ. Influence of provisional cements on ultimate bond strength of indirect composite restorations to dentin. J Adhes Dent. 2005 Autumn;7(3):225-30.

    PMID: 16240963BACKGROUND
  • Hill EE, Lott J. A clinically focused discussion of luting materials. Aust Dent J. 2011 Jun;56 Suppl 1:67-76. doi: 10.1111/j.1834-7819.2010.01297.x.

    PMID: 21564117BACKGROUND
  • Koumjian JH, Nimmo A. Evaluation of fracture resistance of resins used for provisional restorations. J Prosthet Dent. 1990 Dec;64(6):654-7. doi: 10.1016/0022-3913(90)90290-s.

    PMID: 2079670BACKGROUND
  • Mahn E, Rousson V, Heintze S. Meta-Analysis of the Influence of Bonding Parameters on the Clinical Outcome of Tooth-colored Cervical Restorations. J Adhes Dent. 2015 Aug;17(5):391-403. doi: 10.3290/j.jad.a35008.

    PMID: 26525003BACKGROUND
  • Qudeimat MA, Alyahya A, Hasan AA. Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study. Int Endod J. 2017 Feb;50(2):126-134. doi: 10.1111/iej.12614. Epub 2016 Feb 22.

    PMID: 26841969BACKGROUND
  • von Arx T. [Mineral trioxide aggregate (MTA) a success story in apical surgery]. Swiss Dent J. 2016;126(6):573-95. doi: 10.61872/sdj-2016-06-02. French, German.

    PMID: 27377433BACKGROUND
  • Young HM, Smith CT, Morton D. Comparative in vitro evaluation of two provisional restorative materials. J Prosthet Dent. 2001 Feb;85(2):129-32. doi: 10.1067/mpr.2001.112797.

    PMID: 11208201BACKGROUND

MeSH Terms

Interventions

Eugenol

Intervention Hierarchy (Ancestors)

Caffeic AcidsCinnamatesAcids, CarbocyclicCarboxylic AcidsOrganic ChemicalsAllylbenzene DerivativesAllyl CompoundsAlkenesHydrocarbons, AcyclicHydrocarbonsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, Cyclic

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

February 11, 2018

First Posted

February 19, 2018

Study Start

March 20, 2018

Primary Completion

April 30, 2018

Study Completion

October 30, 2018

Last Updated

March 7, 2018

Record last verified: 2018-03

Data Sharing

IPD Sharing
Will not share

Locations