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PI Retirement
Sponsor study identifier
Secondary identifiers
observational
26
1 country
1
Study Start
May 16, 2018
Actual (reported)Primary Completion
August 21, 2025
Actual (reported)Study Completion
August 21, 2025
Actual (reported)Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This may help them find new ways to help children move better. Objectives: To learn more about how infants and young children with and without cerebral palsy use their brain to move their arms and legs. Eligibility: Children ages 3 months - 5 years with and without cerebral palsy Design: Participants will be screened with:
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 21, 2025
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 14, 2018
Actual (reported)February 15, 2018
Actual (reported)May 16, 2018
Actual (reported)August 21, 2025
Actual (reported)August 21, 2025
Actual (reported)Magnitude, extent and location of brain activity recorded by NIRS and/or EEG within tasks across subject groups. We will also quantify changes in brain activation across ages (cross-sectional) and time (longitudinal).
Data from each of the techniques will be compared across subjects group.
each visit
Secondary outcomes include motion and EMG data to help interpret task and group differences and measures of motor abilities. The same outcome measures will be compared across ages to examine the development of cortical activation patterns and mo...
Each Visit
The group with ASD (including all infants less than 3 years of age who are identified as being at high-risk for ASD)
The group with CP (including all infants less than 18 months who are identified as being athigh-risk for CP)
The control group will consist of 50 healthy volunteers with TD
1\. patient diagnosed with Autism or infant at high risk ASD. 2. patient diagnosed with CP or infant under 18 months for being at high risk with CP. 3. Typical Development kids (TD).
National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Diane L Damiano, Ph.D.
National Institutes of Health Clinical Center (CC)
26 participants (actual enrollment reported by the registry).
First Submitted
February 14, 2018
First Posted
February 15, 2018
Study Start
May 16, 2018
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
August 21, 2025
Actual (reported)Study Completion
August 21, 2025
Actual (reported)Last Updated
August 22, 2025
Record last verified: 2025-08
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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