Brief Summary

Inappropriate prescription of unnecessary and potentially harmful medications continues to be a widespread problem for hospitalized patients. The investigators aim to study the prescription patterns of several classes of medications featured both in the Canadian Choosing Wisely campaign and the Beers Criteria for medication1,2. Specifically, this study will be looking at the patterns of sedatives (includes benzodiazepines, sedative-hypnotics, and sedating antipsychotics) prescriptions over time. The investigators aim to determine how closely these recommendations are adhered to on medical-surgical wards at five local hospitals (Sinai Health System, Toronto General Hospital, Toronto Western Hospital, Sunnybrook Health Sciences Center, and St. Michael's Hospital); and to observe trends in prescribing before and after hospital-wide quality improvement initiatives.

Trial Health

On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment

19,090

participants targeted

Target at P75+ for all trials

Timeline

Completed

Started May 2017

Typical duration for all trials

Geographic Reach

1 country

1 active site

Status

completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

2.6 years study duration

Study Start

First participant enrolled

May 19, 2017

Completed

9 months until next milestone

First Submitted

Initial submission to the registry

January 29, 2018

Completed

7 days until next milestone

First Posted

Study publicly available on registry

February 5, 2018

Completed

1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 19, 2019

Completed

Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 19, 2019

Completed

Last Updated

February 20, 2020

Status Verified

February 1, 2020

Enrollment Period

2.6 years

First QC Date

January 29, 2018

Last Update Submit

February 18, 2020

Conditions

Sedative Adverse Reaction Sleep

Outcome Measures

Primary Outcomes (1)

Rates of sedatives prescribed
The primary goal of the study is to determine the rate and trend of inappropriate sedative use and prescription among medical-surgical inpatients over time.
27 months

Secondary Outcomes (1)

Length of Stay
27 months

Study Arms (6)

1

General Medicine in Hospital Unit 70 Bed. Quality Improvement Intervention, prescription reduction The intervention is a quality improvement education aimed at reducing sedative prescriptions and implementing safe sleep environments.