Egg Intake and Risk of Type 2 Diabetes

NCT03406910 | Completed

• 1 other identifier: 2140392
• Study Type: observational
• Target: 55,851
• Locations: 1 country
• Sites: 1

Brief Summary

This is a longitudinal study that will collect demographic, anthropometric and dietary data to determine the relationships between meat and egg intake and the incidence of Type 2 Diabetes.

Conditions

Type 2 Diabetes; Heart Diseases

Keywords

egg; meat; western diet; type 2 diabetes; Adventist Health Study; Vegetarian cohort; Adventist

Outcome Measures

Primary Outcomes (1)

• Risk for Type 2 Diabetes (T2D) in subjects who consume different frequencies/amounts of eggs and meat.

  Validated quantitative food frequency questionnaire that compares risk of T2D in subjects who consume different frequencies /amounts of egg and meat and physician diagnosis of diabetes

  Change between baseline and 5 Years of follow up

Study Arms (1)

Seventh day Adventist adults

Seventh day Adventist adults recruited from the USA and Canada. Approximately 65% female and 35% male. Composed of participants with different dietary patterns and a wide variation in egg and meat intake ranging from non-consumptive to daily consumption.

Eligibility Criteria

• Age: 31 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The AHS-2 is a prospective cohort of \>96,000 Seventh-day Adventist adults recruited from the USA and Canada between February 2002 and May 2007. Designed primarily to examine associations between diet and health outcomes, the study is composed of approximately 65% females and 27% blacks. Recruitment and data collection methods for the parent cohort have been described previously. The cohort is composed of participants with different dietary patterns and a wide variation in egg and meat intake ranging from non-consumption to daily consumption. Approval for the AHS-2 study was obtained from the Loma Linda University Human Subjects Committee Institutional Review Board and written informed consent was acquired from all AHS-2 participants upon enrollment.

You may qualify if:

• AHS 2 Participants who filled out Hospital History Questionnaire version 3 or 5 Age \> 30 years

You may not qualify if:

• Subjects with missing values in dietary variables were excluded from the analytic sample,
• missing gender
• age \< 30 years
• improbable questionnaire response patterns
• extremes of BMI (less than 16 or greater than 60)
• estimated energy intake (less than 500 or greater than 4,500 kcal/d)
• existing cases of type 1 or type 2 diabetes at baseline
• inconsistent reports of T2D between HHQ version 3 and 5

Sponsors & Collaborators

• Loma Linda University: lead
• American Egg Board: collaborator

Study Sites (1)

Loma Linda University

Loma Linda, California, 92350, United States

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2; Heart Diseases

Condition Hierarchy (Ancestors)

Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Cardiovascular Diseases

Study Officials

• Joan Sabate, DrPH

  Loma Linda University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Nutrition and Epidemiology

Study Record Dates

• First Submitted: January 16, 2018
• First Posted: January 23, 2018
• Study Start: February 13, 2015
• Primary Completion: June 30, 2017
• Study Completion: June 30, 2017
• Last Updated: January 23, 2018

Record last verified: 2018-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)