NCT03405116

Brief Summary

A register and prediction model will be developed to predict the outcome of preterm labour and birth.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,037

participants targeted

Target at P75+ for all trials

Timeline
80mo left

Started Jul 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress57%
Jul 2017Dec 2032

Study Start

First participant enrolled

July 1, 2017

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

November 23, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 19, 2018

Completed
5.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2023

Completed
9.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2032

Expected
Last Updated

May 30, 2024

Status Verified

May 1, 2024

Enrollment Period

5.8 years

First QC Date

November 23, 2017

Last Update Submit

May 29, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Register

    A multicentre, multidisciplinary register will be created to provide a source of valuable information on obstetrical and neonatal practices and link them with obstetrical, neonatal and long-term outcomes of preterm labour and birth

    2017 - 2030

  • Prediction model

    The prediction tool for true preterm labour (TPL) will be developed using individual risk factors, symptomatology, tocography, cervical change and a biomarker test, followed by a decision-making model, both based on individual data, evidence and experience.

    2017 - 2030

Secondary Outcomes (1)

  • The interval between starting corticosteroids and delivery

    2012-2020

Eligibility Criteria

Age18 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Women visiting the maternity ward suffering from symptoms of preterm birth.

You may qualify if:

  • Gestational age of 24 weeks 0 days and 33 weeks and 6 days, and their preterm born children

You may not qualify if:

  • Patients who choose not to participate in the research.
  • Intra-uterine prelabour fetal death.
  • Fetuses or neonates with a major congenital disorder. Major is defined as a disorder that has an impact on neonatal respiratory and cerebral outcome and/or long-term outcome.
  • Postpartum transfer/outborn.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ghent University Hospital - Women's Clinic

Ghent, 9000, Belgium

Location

Related Publications (1)

  • Dehaene I, Scheire E, Steen J, De Coen K, Decruyenaere J, Smets K, Roelens K. Obstetrical characteristics and neonatal outcome according to aetiology of preterm birth: a cohort study. Arch Gynecol Obstet. 2020 Oct;302(4):861-871. doi: 10.1007/s00404-020-05673-5. Epub 2020 Jul 3.

MeSH Terms

Conditions

Premature Birth

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Study Officials

  • Kristien Roelens, MD, PhD

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
4 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 23, 2017

First Posted

January 19, 2018

Study Start

July 1, 2017

Primary Completion

May 1, 2023

Study Completion (Estimated)

December 1, 2032

Last Updated

May 30, 2024

Record last verified: 2024-05

Locations