Mind-Body Walking Exercise for Chronic Obstructive Pulmonary Disease

NCT03388489 | Completed

• 1 other identifier: 201312004RIND
• Study Type: interventional
• Target: 84
• Locations: 0 countries
• Sites: N/A

Brief Summary

Mind-body exercise improves symptom of negative moods, dyspnea and quality of life in chronic diseases, but these improvements for chronic obstructive pulmonary disease (COPD) are unproven. This study aims to examine the effects of dyspnea, exercise capacity, heart rate variability(HRV), anxiety, depression, interoceptive awareness, quality of life(QoL) in patients with COPD across a three-month mind-body exercise program.

Conditions

Chronic Obstructive Pulmonary Disease; Exercise; Anxiety; Depression; Dyspnea; Quality of Life; Heart Rate Variability

Outcome Measures

Primary Outcomes (1)

• Change of modified Borg scale for dyspnea level

  The modified Borg scale is a visual tool ranging from 0 (not noticeable) to 10 (maximum dyspnea).

  Baseline and follow up on Week 4, 8, and 12.

Secondary Outcomes (6)

• Heart rate variability (HRV)

  Baseline and follow up on Week 4, 8, and 12.

• Hospital anxiety and depression scale (HADS) for anxiety and depression

  Baseline and follow up on Week 4, 8, and 12.

• The Chinese version multidimensional assessment of interoceptive awareness (MAIA-C) for interoceptive awareness

  Baseline and follow up on Week 4, 8, and 12.

• Six-minute walk distance for exercise capacity

  Baseline and follow up on Week 4, 8, and 12.

• modified Medical Research Council (mMRC) for perception of dyspnea in daily life

  Baseline and follow up on Week 4, 8, and 12.

Study Arms (2)

Mind-Body Walking

EXPERIMENTAL

breathing, walking and meditation

Behavioral: Mind-Body Walking

Usual care

NO INTERVENTION

maintain their daily activity

Interventions

Mind-Body Walking BEHAVIORAL

walking, breathing, and mindfulness

Mind-Body Walking

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• mild to severe COPD

You may not qualify if:

• Patients visited the emergency room or were hospitalized previous month;
• Long-term oxygen therapy;
• Atrial fibrillation;
• Severe cognitive impairment;
• Great than class II heart failure as defined by the New York Heart Association functional classification in previous six months;
• Pacemaker were excluded;
• Received cancer treatment
• Participated in other exercise trials

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Related Publications (1)

• Lin FL, Yeh ML, Lai YH, Lin KC, Yu CJ, Chang JS. Two-month breathing-based walking improves anxiety, depression, dyspnoea and quality of life in chronic obstructive pulmonary disease: A randomised controlled study. J Clin Nurs. 2019 Oct;28(19-20):3632-3640. doi: 10.1111/jocn.14960. Epub 2019 Jun 28.

  PMID: 31192478 DERIVED

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Motor Activity; Anxiety Disorders; Depression; Dyspnea

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Behavior; Mental Disorders; Behavioral Symptoms; Respiration Disorders; Signs and Symptoms, Respiratory; Signs and Symptoms

Study Officials

• Feng-Lien Lin, PhD

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: CARE PROVIDER
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 8, 2017
• First Posted: January 3, 2018
• Study Start: August 18, 2014
• Primary Completion: August 13, 2015
• Study Completion: August 13, 2015
• Last Updated: January 3, 2018

Record last verified: 2013-12

Data Sharing

• IPD Sharing: Will not share