Right Ventricular and Pulmonary Artery Evaluation by CMR
Right Ventricular Geometry, Function, Morphology and Pulmonary Arterial Stiffness and Size Evaluation by Cardiac Magnetic Resonance
1 other identifier
observational
100
1 country
1
Brief Summary
Pulmonary hypertension results in right ventricle dysfunction. Cardiac magnetic resonance derived RV ejection fraction is a prognostic value in this condition. Right ventricular geometry, function, morphology as well as pulmonary arterial stiffness and size may be evaluated by cardiac magnetic resonance imaging and could have great importance in evaluation of pulmonary hypertension prognosis and outcomes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2012
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2017
CompletedFirst Submitted
Initial submission to the registry
December 6, 2017
CompletedFirst Posted
Study publicly available on registry
December 19, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2018
CompletedDecember 19, 2017
December 1, 2017
5.1 years
December 6, 2017
December 14, 2017
Conditions
Outcome Measures
Primary Outcomes (4)
Right ventricle function and morphological changes in pulmonary hypertension patients during follow up
Right ventricle function will be evaluated by CMR at base line and during follow up to find significant values for disease progression and prognosis
2 years
Right ventricle function and morphological changes in pulmonary hypertension patients during follow up
Pulmonary artery will be evaluated by CMR at base line and during follow up to find significant values for disease progression and prognosis
2 years
Left ventricle function and mechanical changes in pulmonary hypertension patients during follow up
Left ventricle function and mechanical changes will be evaluated by CMR and FT at base line and during follow up to find significant values for disease progression and prognosis
2 years
Right ventricle mechanical changes in pulmonary hypertension patients during follow up
Right ventricle function and mechanical changes will be evaluated by FT at base line and during follow up to find significant values for disease progression and prognosis
2 years
Interventions
CMR is performed using a 1,5T whole-body system (Siemens Aera, Siemens Medical Solutions; Erlangen, Germany)
Eligibility Criteria
Precapillary pulmonary hypertesnion patients
You may qualify if:
- Patient with diagnosed pulmonary hypertension
- RHC, 6MWT, echocardiography, NT-pro BNP, CMR performed in one month period.
- Patients who signed study informed consent form.
You may not qualify if:
- Coronary and valvular heart disease
- Atrial fibrillation
- Expressed shortness of breath
- Claustrophobia.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
LSMU
Kaunas, LT44307, Lithuania
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Lina Padervinskiene, PhD
LSMU
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Professor
Study Record Dates
First Submitted
December 6, 2017
First Posted
December 19, 2017
Study Start
January 1, 2012
Primary Completion
February 1, 2017
Study Completion
November 1, 2018
Last Updated
December 19, 2017
Record last verified: 2017-12