The Utility of Platelet Rich Plasma in Hair Loss
1 other identifier
interventional
30
1 country
1
Brief Summary
Platelet rich plasma (PRP) is an autologous preparation of human plasma with high concentration of platelets. Platelets release numerous growth factors, which stimulate cell proliferation and differentiation. The purpose of this research is to investigate the potential of PRP injection for treatment of hair loss. Clinical outcomes will be assessed by noninvasive techniques including dermoscopy, multiphoton microscopy, optical coherence tomography, optical Doppler tomography and multispectral imaging.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for early_phase_1
Started Nov 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 28, 2017
CompletedFirst Submitted
Initial submission to the registry
December 13, 2017
CompletedFirst Posted
Study publicly available on registry
December 18, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 20, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
February 20, 2019
CompletedFebruary 2, 2024
February 1, 2024
1.2 years
December 13, 2017
February 1, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Hair density to measure the efficacy of treatment
6 months
Secondary Outcomes (6)
Hair count (number of hairs/0.65 cm2)
6 months
Terminal hair density
6 months
Anagen hair percentage
6 months
Telogen hair percentage
6 months
Anagen/telogen ratio
After 3 and 6 months
- +1 more secondary outcomes
Study Arms (1)
Prospective treatment
EXPERIMENTALInterventions
Blood drawn from each participant will be spun down to separate platelets. Platelets will be injected into that patient's scalp.
Eligibility Criteria
You may qualify if:
- Over 18 years of age
- Ability to understand and carry out instructions
- Diagnosed with alopecia
You may not qualify if:
- Inability to understand and.or carry out instructions
- Pregnant women
- Use of any topical medication (such as minoxidil or any other solution for hair growth), oral medication (finasteride, dutasteride, or antiandrogens), laser therapy, or chemotherapy, within the preceding 4 weeks.
- Personal medical history of bleeding disorders
- Personal medical history of platelet dysfunction syndrome
- Anti-coagulation therapy or nonsteroidal anti-inflammatory drugs in the last 1 week.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of California, Irvine, Department of Dermatology, Dermatology Clinical Research Center, Hewitt Hall
Irvine, California, 92697, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- early phase 1
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
December 13, 2017
First Posted
December 18, 2017
Study Start
November 28, 2017
Primary Completion
February 20, 2019
Study Completion
February 20, 2019
Last Updated
February 2, 2024
Record last verified: 2024-02