Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women

NCT03372876 | Completed

• 1 other identifier: 2.023.127
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluated the effect of protein intake immediately after resistance exercise on lean mass, strength, and functional capacity gains in postmenopausal women. Participants were randomly assigned to protein-carbohydrate group (PC) (n=17), that ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon; and to carbohydrate-protein group (CP) (n=17), that ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. Both groups performed the same resistance training protocol in the morning.

Conditions

Sarcopenia

Outcome Measures

Primary Outcomes (1)

• Changes in the lean mass of postmenopausal women practicing resistance exercise

  Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)

Secondary Outcomes (2)

• Changes on strength of postmenopausal women practicing resistance exercise

  Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)

• Changes on functional capacity of postmenopausal women practicing resistance exercise

  Before and immediately after the intervention (initial moment and 8 weeks after start of the intervention)

Study Arms (2)

Protein-carbohydrate (PC) (protein intake after exercise)

EXPERIMENTAL

ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon. The resistance exercise was performed equally by both groups.

Dietary Supplement: Protein and carbohydrate supplementation

Carbohydrate-protein (CP) (protein intake far to exercise)

PLACEBO COMPARATOR

ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. The resistance exercise was performed equally by both groups.

Dietary Supplement: Protein and carbohydrate supplementation

Interventions

Protein and carbohydrate supplementation DIETARY_SUPPLEMENT

Participants were randomly assigned to protein-carbohydrate group (PC) (n=17), that ingested 30 g of whey protein immediately after exercise and 30 g of maltodextrin in the afternoon; and to carbohydrate-protein group (CP) (n=17), that ingested 30 g of maltodextrin immediately after exercise and 30 g of whey protein in the afternoon. Both groups performed the same resistance training protocol in the morning, 3 times a week, at 70% of 1-maximum repetition (1-RM) during 8 weeks.

Also known as: Resistance exercise

Carbohydrate-protein (CP) (protein intake far to exercise); Protein-carbohydrate (PC) (protein intake after exercise)

Eligibility Criteria

• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased);
• Healthy;
• Who agree to participate and sign the consent term.

You may not qualify if:

• The one who does not provide the necessary information for the development of the study;
• Present orthopedic limitations;
• Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.

Sponsors & Collaborators

• Federal University of Uberlandia: lead

Study Sites (1)

Erick P. de Oliveira

Uberlândia, Minas Gerais, 38.405-320, Brazil

Location

Related Publications (1)

• de Branco FMS, Carneiro MAS, Rossato LT, Nahas PC, Teixeira KRC, de Oliveira GN Jr, Orsatti FL, de Oliveira EP. Protein timing has no effect on lean mass, strength and functional capacity gains induced by resistance exercise in postmenopausal women: A randomized clinical trial. Clin Nutr. 2020 Jan;39(1):57-66. doi: 10.1016/j.clnu.2019.01.008. Epub 2019 Jan 17.

  PMID: 30691866 DERIVED

MeSH Terms

Conditions

Sarcopenia

Interventions

Proteins; Resistance Training

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Amino Acids, Peptides, and Proteins; Exercise Therapy; Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities; Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD

Study Record Dates

• First Submitted: December 10, 2017
• First Posted: December 14, 2017
• Study Start: May 8, 2017
• Primary Completion: October 4, 2017
• Study Completion: October 11, 2017
• Last Updated: December 15, 2017

Record last verified: 2017-12

Data Sharing

• IPD Sharing: Will not share

Locations

BR (1)