Neuro-cognitive Bases of Joint Action
Basi Neuro-cognitive Dell'Interazione Motoria
1 other identifier
interventional
50
1 country
1
Brief Summary
The ability to interact with conspecifics is crucial in life, yet there is no consensus on the underlying cognitive and neural mechanisms beyond those associated with imitative behaviors. This project aims to define a coherent model of non-imitative (complementary) motor interactions. The investigators hypothesize that these might be substantially based on the ability to integrate one's own and a partner's action within a unitary, dual- person (dyadic), motor plan that incorporates a shared goal. With a novel "minimally-joint" paradigm the investigators will test this hypothesis and measure with behavioral measures (i.e., reaction times) whether the supposedly automatic tendency to imitate others is modulated by the need to coordinate with a partner to achieve a shared goal. This paradigm will be also applied during a functional MRI experiment to describe the underlying neurophysiological patterns; using dynamic causal modeling the investigators will measure how the brain regions relevant for dyadic motor control are functionally linked. This converging experimental strategy will permit to compare competing psychological and neural models of motor interactions in healthy participants, opening new experimental avenues for studies in adult neuropsychological patients and in children with typical and atypical social development.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Apr 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2017
CompletedFirst Submitted
Initial submission to the registry
November 21, 2017
CompletedFirst Posted
Study publicly available on registry
December 12, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 20, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
December 20, 2019
CompletedAugust 10, 2018
August 1, 2018
1.7 years
November 21, 2017
August 8, 2018
Conditions
Outcome Measures
Primary Outcomes (2)
Reaction Times
The investigators will compare Reaction Times of participants recorded during Joint Action with those recorded in Non-Joint individual condition.
1 year
BOLD activations
The investigators will study the neurofunctional activations indexed by the Blood Oxygen Level Dependent (BOLD) recorded during Joint Action will be compared to the Non-Joint actions
1 year
Study Arms (1)
Healthy Subjects
EXPERIMENTALHealthy Subjects take part in the experimental manipulation
Interventions
The neurofunctional correlates of motor control will be compared between a collaborative and non-interactive condition.
Eligibility Criteria
You may qualify if:
- right handed; no contraindication to MRI
You may not qualify if:
- contraindication to MRI
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
IRCCS Galeazzi Orthopedic Hospital
Milan, 20161, Italy
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 21, 2017
First Posted
December 12, 2017
Study Start
April 1, 2017
Primary Completion
December 20, 2018
Study Completion
December 20, 2019
Last Updated
August 10, 2018
Record last verified: 2018-08