Nonalcoholic Fatty Liver Disease is Associated With Increased Atrial Fibrillation Risk in an Elderly Chinese Population

NCT03366987 | Completed

• 1 other identifier: Ningbo2
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

Atrial fibrillation and nonalcoholic fatty liver disease are two pathological conditions that are highly prevalent worldwide and share multiple CVD risk factors. There is rare research performed among elderly adults. The investigators are conducting a cross-sectional analysis of elderly adults (≥65 years) to investigate the association between atrial fibrillation and nonalcoholic fatty liver disease in an elderly Chinese population.

Conditions

Nonalcoholic Fatty Liver Disease; Atrial Fibrillation; Cross-sectional Study

Outcome Measures

Primary Outcomes (1)

• Association of nonalcoholic fatty liver disease and atrial fibrillation

  The association of nonalcoholic fatty liver disease and atrial fibrillation by chi-square test.

  the physical examination data in the year of 2014

Secondary Outcomes (2)

• Prevalence of AF in an elderly Chinese population stratified by normal or elevated serum liver enzyme concentration

  the physical examination data in the year of 2014

• Prevalence of AF in an elderly Chinese population stratified by NAFLD status on ultrasound combined with normal or elevated serum AST/ALT/GGT concentration

  the physical examination data in the year of 2014

Eligibility Criteria

• Age: 65 Years - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The elderly adults (≥65 years old) who had undergone an annual physical examination at Zhenhai Lianhua Hospital, Ningbo, China in 2014

You may qualify if:

• those who undergone an annual physical examination at Zhenhai Lianhua Hospital, Ningbo, China in 2014
• elderly adults (≥65 years old)

You may not qualify if:

• unknown alcohol intake or excessive alcohol intake
• unknown BMI or BMI≤18.0kg/m2
• incomplete basic physical data
• missing liver ultrasonic diagnosis
• unknown causes of chronic liver disease

Sponsors & Collaborators

• Ningbo No. 1 Hospital: lead

Study Sites (1)

Ningbo NO.1 hospital

Ningbo, Zhejiang, 315010, China

Location

MeSH Terms

Conditions

Non-alcoholic Fatty Liver Disease; Atrial Fibrillation

Condition Hierarchy (Ancestors)

Fatty Liver; Liver Diseases; Digestive System Diseases; Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Lei Xu, Dr.

  Department of Gastroenterology, Ningbo No. 1 Hospital, Ningbo, China

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 26, 2017
• First Posted: December 8, 2017
• Study Start: December 12, 2017
• Primary Completion: January 18, 2018
• Study Completion: January 30, 2018
• Last Updated: June 21, 2019

Record last verified: 2018-07

Locations

CN (1)