Prevalence, Impact and Predictors of Chronic Postoperative Pain

NCT03363672 | Unknown

• 1 other identifier: PUMCH-CPP
• Study Type: observational
• Target: 500
• Locations: 0 countries
• Sites: N/A

Brief Summary

Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem, which could last for more than 3 months after surgery. The aim of present study was to assess the prevalence of CPP, investigate its impact on life quality and explore its potential risk factors. After informed consent was signed, patients receiving surgery under general anesthesia in Peking Union Medical College Hospital and other medical centers participating in this study during 2018 will be included. Patients' preoperative information will be collected from medical record, including basic demographic data, primary disease and previous chronic diseases. Intraoperative information will be obtained from anesthesia record, including surgical scope, duration, length and location of incisions and blood loss. Acute pain will be evaluated in the ward of the department of surgery, when an app will be installed on patients' mobile phones. Our long-term postoperative follow-up would be performed by sending out survey questionnaires via this app in the 4th, 8th, 16th, 32th, and 48th weeks after surgery. The survey covers questions regarding the intensity, characteristic, location and impact on daily activities of CPP. Information regarding treatment of CPP will also be collected, if any. All the data gained will be summarized in our database and analyzed.

Conditions

Chronic Postoperative Pain

Keywords

Chronic Postoperative Pain; Daily Life; Risk Factor

Outcome Measures

Primary Outcomes (1)

• The prevalence of chronic postoperative pain

  The prevalence of chronic postoperative pain reported by the included patients in the questionnaire issued by app

  24 weeks postoperatively

Secondary Outcomes (4)

• The prevalence of chronic postoperative pain

  4,8,12,16,20,32,40,48 weeks postoperatively

• Wong-Baker Faces Pain Rating Scale

  4,8,12,16,20,24,32,40,48 weeks postoperatively

• Characteristics and location of chronic postoperative pain

  4,8,12,16,20,24,32,40,48 weeks postoperatively

• Brief Pain Index

  4,8,12,16,20,24,32,40,48 weeks postoperatively

Study Arms (1)

Patients receiving surgery

No intervention will be administered. Patients included will be asked to return a questionnaire regarding chronic postoperative pain via app.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients receiving surgery under general anesthesia during 2018 in Peking Union Medical College Hospital and other medical centers participating in this study

You may qualify if:

• Patients receiving surgery under general anesthesia during 2018 in Peking Union Medical College Hospital and other medical centers participating in this study.
• Aged 18-70 years.

You may not qualify if:

• Previous surgery history;
• Preoperative chronic pain history;
• Injury;
• Have no access to mobile phone or website;
• Postoperative chronic infection;
• Non-radical incision of tumor or malignancy recurrence during follow-up;

Sponsors & Collaborators

• Peking Union Medical College Hospital: lead

MeSH Terms

Conditions

Pain, Postoperative

Condition Hierarchy (Ancestors)

Postoperative Complications; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Pain; Neurologic Manifestations; Signs and Symptoms

Study Officials

• Yuguang Huang, MD.

  Peking Union Medical College Hospital

  STUDY CHAIR

Central Study Contacts

Yuguang Huang, MD.

CONTACT

86-10-69152066; garypumch@163.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 48 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chairman of anesthesisology department

Study Record Dates

• First Submitted: November 20, 2017
• First Posted: December 6, 2017
• Study Start: January 1, 2018
• Primary Completion: December 31, 2019
• Study Completion: December 31, 2019
• Last Updated: December 6, 2017

Record last verified: 2017-11

Data Sharing

• IPD Sharing: Will share
• Time Frame: IPD will become available from 2018-1-1 to 2019-12-31.
• Access Criteria: All the IPD will be included in a public database shared by all the medical centers participating in this study.