NCT03359629

Brief Summary

Diabetes mellitus (or diabetes) is a chronic, metabolic disease characterized by elevated levels of blood glucose. Patients with diabetes need to monitor their blood glucose level several times a day to control their medical state. Modern biosensors have become a promising solution for non-invasive blood glucose measurements. This study aims to validate the efficacy and the accuracy of Glucometry Monitor (NIGM) developed by Spectrophon LTD incorporated in smart watches. Method Participants will use Spectrophon biosensors to non-invasively estimate the level of glucose in blood. Blood will also be collected and the glucose level will be checked with commercially available blood glucose analyzers . All sets of data will be compared to estimate the accuracy of measurements of Spectrophon NIGM

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 27, 2017

Completed
18 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2017

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 16, 2017

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

November 23, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 2, 2017

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

March 7, 2019

Completed
Last Updated

March 7, 2019

Status Verified

November 1, 2018

Enrollment Period

18 days

First QC Date

November 23, 2017

Results QC Date

December 18, 2017

Last Update Submit

November 9, 2018

Conditions

Keywords

SpectrophonGlucoseBiosensorNon-invasive testing

Outcome Measures

Primary Outcomes (1)

  • Percentage of Measurements With < 15% Error

    Difference in measurements of blood glucose level obtained using Spectrophon glucometry monitor and commercially available glucose analyser YSI 2300

    1-3 hours

Interventions

Wearable smartwatch with integrated non-invasive glucose detection system

Reference commercial glucometer

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Israeli and non-israeli citizens of age 18-75.

You may qualify if:

  • must be between ages 18 and 75
  • must be able to sign informed consent form.

You may not qualify if:

  • Acute psychotic state
  • Hepatitis
  • HIV
  • Tuberculosis
  • Haemophilia and other serious coagulation disorders
  • Significant impaired venous access
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tirat Carmel Mental Health Center

Tirat Carmel, Haifa District, 30200, Israel

Location

MeSH Terms

Conditions

Glucose Metabolism DisordersDiabetes Mellitus

Condition Hierarchy (Ancestors)

Metabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Results Point of Contact

Title
Anatoly Kreinin
Organization
Maale Carmel Mental Health Center

Study Officials

  • Anatoly Kreinin, MD, PHD

    Bruce Rappaport Medical Faculty, Technion, Haifa, Israel

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Assistant Professor

Study Record Dates

First Submitted

November 23, 2017

First Posted

December 2, 2017

Study Start

September 27, 2017

Primary Completion

October 15, 2017

Study Completion

October 16, 2017

Last Updated

March 7, 2019

Results First Posted

March 7, 2019

Record last verified: 2018-11

Locations