Prognostic Value of Serum Cholesterol and Triglyceride in Septic and Non Septic Patients

NCT03359369 | Completed

• 1 other identifier: doaa rashwan
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The primary outcome of this study is to evaluate the difference between the level of serum cholesterol and triglyceride in septic and non septic patients in the ICU. . The secondary outcome will be to find correlation between the level of serum cholesterol and triglyceride and both Acute physiology And Chronic Health Evaluation Score (APACHE) II(19) and quick Sequential Organ Failure Assessment (qSOFA) score (20) and their relation to mortality.

Conditions

Septic Patients; Nonseptic Patients

Outcome Measures

Primary Outcomes (1)

• change in the level of serum cholesterol and triglyceride

  change in the level of serum cholesterol and triglyceride

  on days 0, 1, 3, and 7, 10 and 14 days

Study Arms (2)

Septic Patients

Diagnostic Test: level of serum cholesterol and triglyceride

Non Septic Patients

Diagnostic Test: level of serum cholesterol and triglyceride

Interventions

level of serum cholesterol and triglyceride DIAGNOSTIC_TEST

other

Non Septic Patients; Septic Patients

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population will include the patients (age range between 20 and 70) of both sex (septic and non septic patients e.g. trauma patients, post surgical patients) who will be admitted to the surgical intensive care in Beni-Suef University hospital

You may qualify if:

• The study population will include the patients (age range between 20 and 70) of both sex (septic and non septic patients e.g. trauma patients, post surgical patients) who will be admitted to the surgical intensive care in Beni-Suef University hospital

You may not qualify if:

• Age less than 20
• Pregnancy
• ICU readmission
• Dyslipidemia
• Patients with liver disease e.g.hepatitis B,hepatitis C , liver cirrhosis, and hepatocellular carcinoma)
• Concomitant of use immunosuppressive therapy
• Using statin or steroid (≥15mg/day) within the previous 7 days
• Patients who had been treated with corticosteroid therapy for septic shock prior to admission to ICU
• Patients sedated by propofol

Sponsors & Collaborators

• Beni-Suef University: lead

Study Sites (1)

Faculty Of Medicine, Beni-Suef University

Banī Suwayf, 11391, Egypt

Location

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: November 24, 2017
• First Posted: December 2, 2017
• Study Start: January 7, 2018
• Primary Completion: November 13, 2018
• Study Completion: December 13, 2018
• Last Updated: January 3, 2019

Record last verified: 2018-12

Locations

EG (1)