Cardiovascular Disease Cohort in Guangdong Province
Prospective Cohort Study of Cardiovascular Disease in Guangdong Province
1 other identifier
observational
5,000
1 country
1
Brief Summary
Patients with cardiovascular diseases from Guangdong province will be recruited and followed up for at least 4 years to evaluate the risk factors for cardiovascular-related mortality and disability. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of all-cause and cardiovascular mortality will be investigated during follow-up.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2017
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2017
CompletedFirst Submitted
Initial submission to the registry
November 20, 2017
CompletedFirst Posted
Study publicly available on registry
November 24, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2030
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 31, 2030
May 5, 2022
May 1, 2022
13.2 years
November 20, 2017
May 3, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
All-Cause Mortality
All-cause mortality was confrmed through a combination of hospital medical records, telephone contacts with patients or family members, and death registration at the Guangdong Provincial Center for Disease Control and Prevention.
4 years
Secondary Outcomes (1)
Cardiovascular Mortality
4 years
Eligibility Criteria
Cardiovascular disease patients (30-85 years old) who have been living in Guangdong province for more than 5 years.
You may qualify if:
- Cardiovascular disease patients (30-85 years old) who have been living in Guangdong province for more than 5 years.
- Patients have been diagnosed with primary hypertension, coronary heart disease, heart failure or peripheral vascular disease, etc.
You may not qualify if:
- Patients with cardiogenic (acute pericarditis, rheumatic coronary arteritis, hypertrophic cardiomyopathy, etc.) Or non-cardiogenic chest pain.
- any subject who suffer from malignant tumors, infectious diseases, advanced liver disease, major disability and cannot participate in the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Min Xialead
Study Sites (1)
Sun Yat-Sen University
Guangzhou, Guangdong, 510080, China
Related Publications (1)
Li X, Lin Y, Wang S, Zhou S, Ju J, Wang X, Chen Y, Xia M. Extracellular Superoxide Dismutase Is Associated With Left Ventricular Geometry and Heart Failure in Patients With Cardiovascular Disease. J Am Heart Assoc. 2020 Aug 4;9(15):e016862. doi: 10.1161/JAHA.120.016862. Epub 2020 Jul 29.
PMID: 32750295DERIVED
Biospecimen
Serum, Plasma, Urine and fecal samples for biochemical tests, biomarker examination and DNA extraction
MeSH Terms
Conditions
Study Officials
- PRINCIPAL INVESTIGATOR
Min Xia
School of Public Health,Nutrition and Food Hygiene,Sun Yat-sen University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professer
Study Record Dates
First Submitted
November 20, 2017
First Posted
November 24, 2017
Study Start
November 1, 2017
Primary Completion (Estimated)
December 31, 2030
Study Completion (Estimated)
December 31, 2030
Last Updated
May 5, 2022
Record last verified: 2022-05
Data Sharing
- IPD Sharing
- Will not share