NCT02536456

Brief Summary

China PEACE Millions Persons Project is a national screening project for cardiovascular disease in China. This Project was approved by National Health and Family Planning Commission (NHFPC), China and founded by Ministry of Finance, China in 2014. The specific objectives of the project are to:

  1. 1.identify subjects at high-risk of CVD and provide counseling for medication and lifestyle improvements
  2. 2.evaluate the feasibility of such screening methods for subjects at high risk of CVD, and to assess the effect of health counseling on CVD incidence rates and risk factors control
  3. 3.inform future intervention and long-term follow up efforts for primary and secondary CVD prevention in China.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
4,000,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2014

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2014

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

August 24, 2015

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 31, 2015

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2021

Completed
Last Updated

August 17, 2020

Status Verified

August 1, 2020

Enrollment Period

7 years

First QC Date

August 24, 2015

Last Update Submit

August 13, 2020

Conditions

Cardiovascular Disease

Keywords

screeningcounselingfollow-upcardiovascular diseasepopulation-based projectChina

Outcome Measures

Primary Outcomes (1)

  • Incidence of Cardiovascular diseases

    Number of new cardiovascular diseases in high-risk subjects

    5 years

Eligibility Criteria

Age35 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Residents from the communities or villages in selected sites

You may qualify if:

  • years old
  • registered in the Hukou of the selected region
  • sign the consent form

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fuwai hospital

Beijing, Beijing Municipality, China

RECRUITING

Related Publications (5)

  • Liu X, Lin S, Zhang H, Zhang X, Wu C, Chen B, Yang Y, Cui J, Xu W, Song L, Yang H, He W, Zhang Y, Li X, Lu J. Association of HDL subclass components with all-cause and cardiovascular mortality: a prospective cohort study based on the ChinaHEART project. Lipids Health Dis. 2026 Jan 27. doi: 10.1186/s12944-026-02874-w. Online ahead of print.

    PMID: 41593465DERIVED

  • Wang Y, Peng K, Xu W, Huang X, Liu X, Li Y, Lu J, Yang Y, Chen B, Shi Y, Han G, Zhang X, Cui J, Song L, Tian A, Runsi W, Wang C, Tian Y, Wu Y, Lin C, Peng W, Li X, Hu S. Cardiovascular disease-specific and all-cause mortality across socioeconomic status and lifestyles among patients with established cardiovascular disease in communities of China: data from a national population-based cohort. Heart. 2025 Oct 29;111(22):1092-1100. doi: 10.1136/heartjnl-2024-324766.

    PMID: 40081938DERIVED

  • Wang R, Wang Y, Lu J, Li Y, Wu C, Yang Y, Cui J, Xu W, Song L, Yang H, He W, Zhang Y, Zhang X, Li X, Hu S. Forecasting cardiovascular disease risk and burden in China from 2020 to 2030: a simulation study based on a nationwide cohort. Heart. 2025 Feb 12;111(5):205-211. doi: 10.1136/heartjnl-2024-324650.

    PMID: 39638429DERIVED

  • China PEACE Collaborative Group; Zhou T, Wang Y, Zhang H, Wu C, Tian N, Cui J, Bai X, Yang Y, Zhang X, Lu Y, Spatz ES, Ross JS, Krumholz HM, Lu J, Li X, Hu S. Primary care institutional characteristics associated with hypertension awareness, treatment, and control in the China PEACE-Million Persons Project and primary health-care survey: a cross-sectional study. Lancet Glob Health. 2023 Jan;11(1):e83-e94. doi: 10.1016/S2214-109X(22)00428-4.

    PMID: 36521957DERIVED

  • Lu J, Xuan S, Downing NS, Wu C, Li L, Krumholz HM, Jiang L. Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) Million Persons Project pilot. BMJ Open. 2016 Jan 4;6(1):e010200. doi: 10.1136/bmjopen-2015-010200.

    PMID: 26729395DERIVED

Biospecimen

Retention: SAMPLES WITH DNA

For each high-risk subject, a 6mL whole blood sample is collected in an EDTA vacuum tube.A 10mL urine sample is also collected.

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

  • Lixin Jiang, MD, PhD

    China National Center for Cardiovascular Diseases

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jiapeng Lu, PhD

CONTACT

0086-10-60866783jiapeng.lu@fwoxford.org

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 24, 2015

First Posted

August 31, 2015

Study Start

July 1, 2014

Primary Completion

July 1, 2021

Study Completion

July 1, 2021

Last Updated

August 17, 2020

Record last verified: 2020-08

Locations

CN(1)