NCT03349398

Brief Summary

Uncut Roux-en-Y vs Roux-en-Y reconstruction after distal gastrectomy for gastric cancer

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
84

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 10, 2017

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

November 12, 2017

Completed
9 days until next milestone

First Posted

Study publicly available on registry

November 21, 2017

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2020

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 2, 2020

Completed
Last Updated

April 16, 2020

Status Verified

April 1, 2020

Enrollment Period

2.6 years

First QC Date

November 12, 2017

Last Update Submit

April 15, 2020

Conditions

Keywords

Uncut Roux-en-YRoux-en-Y

Outcome Measures

Primary Outcomes (1)

  • the incidence of Roux stasis syndrome

    the incidence of Roux stasis syndrome after Roux-en-Y reach an incidence of over 30% which involve nausea, vomiting, and abdominal distension. So the incidence of both reconstructions should be compared.

    3 month after surgery

Secondary Outcomes (2)

  • the incidence of other complications after operation

    one month after surgery

  • the quility of life according to the RGB standards

    12 month after surgery

Study Arms (2)

the group of Roux-en-Y

ACTIVE COMPARATOR
Procedure: Roux-en-Y reconstruction

the group of Uncut Roux-en-Y

EXPERIMENTAL
Procedure: Uncut Roux-en-Y reconstruction

Interventions

Uncut Roux-en-Y Reconstruction All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Uncut Roux-en-Y construction will be used in this group.

the group of Uncut Roux-en-Y

Roux-en-Y Reconstruction All surgical procedures will be performed by the single surgery team ,which is leaded by professor Wang Quan. Roux-en-Y construction will be used in this group.

the group of Roux-en-Y

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical diagnosis of distal gastric cancer
  • underwent laparoscopy-assisted distal gastrectomy

You may not qualify if:

  • have simultaneously other cancer
  • have severe systemic inflammatory disease ,serious illness such as diabetes, chronic lung diseases
  • have upper gastrointestinal surgery
  • can't bear the gastric tube
  • the period is too late or the tumor is too large to carry on a laparoscopy assisted radical distal gastrectomy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

the First Hospital of Jilin University

Ch’ang-ch’un, Jilin, 130021, China

RECRUITING

Related Publications (1)

  • Cai Z, Mu M, Ma Q, Liu C, Jiang Z, Liu B, Ji G, Zhang B. Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer. Cochrane Database Syst Rev. 2024 Feb 29;2(2):CD015014. doi: 10.1002/14651858.CD015014.pub2.

MeSH Terms

Conditions

Stomach Neoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach Diseases

Study Officials

  • Quan Wang, Doctor

    The First Hospital of Jilin University

    STUDY DIRECTOR

Central Study Contacts

Quan Wang, Professor

CONTACT

Dong Yang, Master

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assisted Investigator

Study Record Dates

First Submitted

November 12, 2017

First Posted

November 21, 2017

Study Start

November 10, 2017

Primary Completion

June 1, 2020

Study Completion

June 2, 2020

Last Updated

April 16, 2020

Record last verified: 2020-04

Data Sharing

IPD Sharing
Will not share

Locations