NCT03337776

Brief Summary

It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries1. In Hong Kong, colorectal cancer ranks first in cancer incidence and second in cancer mortality based on data from 20142. Recent guidelines from USA, Europe and Asia Pacific region recommend CRC screening for average-risk asymptomatic individuals starting at age 503-5. Modalities such as guaiac-based fecal occult blood tests (gFOBT), fecal immunochemical tests (FIT), flexible sigmoidoscopy (FS), and colonoscopy are among the acceptable options for CRC screening3-5. Department of Health of Hong Kong launched a Colorectal Cancer Screening Pilot Program in late 2016. This is a subsidized program offering primary care consultation with FIT. For those subjects with FIT positive, colonoscopy specialist consultation and colonoscopy will be arranged. The local uptake rate of CRC screening was reported to be 24.5%8 , which is relatively low when compared to other developed county9. In recent years, social media (SM) has become an increasingly popular source of health information10. By providing an easily accessible and interactive channel of communication between reviewers and information providers, it has potential values for affecting public health. However, the effects of SM on uptake of CRC screening has not yet been studied. WhatsApp Messenger, is the most popular social media messaging app worldwide. This randomized controlled study will investigate the effect of WhatsApp vs telephone intervention on the uptake of CRC screening.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Feb 2019

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 6, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 9, 2017

Completed
1.2 years until next milestone

Study Start

First participant enrolled

February 1, 2019

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

August 5, 2021

Status Verified

August 1, 2021

Enrollment Period

10 months

First QC Date

November 6, 2017

Last Update Submit

August 2, 2021

Conditions

Keywords

WhatsApp messengercrc screeningscreening update rate

Outcome Measures

Primary Outcomes (1)

  • CRC screening uptake rate

    Number of subjects participating in CRC screening after study intervention divided by the total number of subjects in each study arm

    1 year

Study Arms (2)

WhatsApp message

ACTIVE COMPARATOR

WhatsApp messages will be sent to invite subjects to participate CRC screening

Other: WhatsApp message

Telephone call

ACTIVE COMPARATOR

Telephone call will be made to invite subjects to participate CRC screening

Other: Telephone call

Interventions

WhatsApp message will be sent to invite subjects to participate in CRC screening

WhatsApp message

Telephone call will be made to invite subjects to participate in CRC screening

Telephone call

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age between 50 - 70
  • Asymptomatic

You may not qualify if:

  • Lack of access to WhatsApp messenger

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Prince of Wales Hospital

Hong Kong, Hong Kong

Location

Study Officials

  • Yuen Tung Thomas Lam, MSc

    Chinese University of Hong Kong

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Nursing Officer

Study Record Dates

First Submitted

November 6, 2017

First Posted

November 9, 2017

Study Start

February 1, 2019

Primary Completion

December 1, 2019

Study Completion

December 31, 2019

Last Updated

August 5, 2021

Record last verified: 2021-08

Locations