Key Insights

Highlights

Success Rate

76% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

10.0%

5 terminated out of 50 trials

Success Rate

76.2%

-10.3% vs benchmark

Late-Stage Pipeline

2%

1 trials in Phase 3/4

Results Transparency

63%

10 of 16 completed with results

Key Signals

10 with results76% success

Data Visualizations

Phase Distribution

43Total
Not Applicable (7)
Early P 1 (1)
P 1 (26)
P 2 (8)
P 3 (1)

Trial Status

Completed16
Recruiting14
Unknown6
Terminated5
Active Not Recruiting4
Not Yet Recruiting4

Trial Success Rate

76.2%

Benchmark: 86.5%

Based on 16 completed trials

Clinical Trials (50)

Showing 20 of 20 trials
NCT06728072Phase 2Recruiting

Addition of Antibiotics to Upfront Treatment Regimen for Colorectal Cancer

NCT07397338Phase 1Recruiting

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

NCT03336658CompletedPrimary

Intratumoral Budding (ITB) in Preoperative Biopsies of Colon and Rectal Cancer

NCT07283367Phase 1RecruitingPrimary

A Phase Ib/II Trial of HS-20110 Combination Therapies in Advanced Colorectal Cancer Patients.

NCT04981119Recruiting

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

NCT07381309Phase 2Not Yet RecruitingPrimary

Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM

NCT04868773Phase 1Completed

Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy

NCT06445062Phase 1Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

NCT07321106Phase 1Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

NCT06657222Phase 1Recruiting

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT07349537Phase 1Recruiting

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

NCT05002270Phase 1Completed

JAB-21822 Activity in Adult Patients With Advanced Solid Tumors Harboring KRAS G12C Mutation

NCT06106308Phase 2Active Not Recruiting

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

NCT05668585Phase 1Completed

A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors

NCT07204574Phase 1RecruitingPrimary

The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer

NCT06682793Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

NCT05980182Not ApplicableCompleted

Engaging Black Men in Colorectal Cancer Screening

NCT05259696Phase 1Completed

Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)

NCT05167071Phase 1Active Not Recruiting

HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study

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Research Network

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