General Anesthetic Mode and Postoperative Complications
Relationship Between General Anesthetic Mode and Postoperative Severe Cardiovascular and Cerebrovascular Complications: a Retrospective Cohort Study
1 other identifier
observational
50,000
0 countries
N/A
Brief Summary
The relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2016
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 31, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
October 10, 2017
CompletedFirst Submitted
Initial submission to the registry
October 30, 2017
CompletedFirst Posted
Study publicly available on registry
November 7, 2017
CompletedNovember 7, 2017
November 1, 2017
7 months
October 30, 2017
November 3, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Major cardiac complication
major cardiac event
90 days after surgery
Study Arms (2)
non-MACE
patients without major postoperative cardiac or cerebral complications
MACE
patients with major postoperative cardiac or cerebral complications
Interventions
Different combination of opioids and anesthetics
Eligibility Criteria
patients for non-cardiac surgery under general anesthesia
You may qualify if:
- non-cardiac surgery, with age\> = 18 years old, ASA grade I-IV, under general anesthesia
You may not qualify if:
- non-general anesthesia, without the use of target-controlled infusion of remifentanil or sufentanil, absence of intraoperative or perioperative information.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (4)
Herling SF, Dreijer B, Wrist Lam G, Thomsen T, Moller AM. Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted laparoscopic surgery. Cochrane Database Syst Rev. 2017 Apr 4;4(4):CD011387. doi: 10.1002/14651858.CD011387.pub2.
PMID: 28374886BACKGROUNDFlier S, Post J, Concepcion AN, Kappen TH, Kalkman CJ, Buhre WF. Influence of propofol-opioid vs isoflurane-opioid anaesthesia on postoperative troponin release in patients undergoing coronary artery bypass grafting. Br J Anaesth. 2010 Aug;105(2):122-30. doi: 10.1093/bja/aeq111. Epub 2010 Jun 23.
PMID: 20573633BACKGROUNDMin JJ, Kim G, Lee JH, Hong KY, Kim WS, Lee YT. Does the Type of Anesthetic Technique Affect In-Hospital and One-Year Outcomes after Off-Pump Coronary Arterial Bypass Surgery? PLoS One. 2016 Apr 7;11(4):e0152060. doi: 10.1371/journal.pone.0152060. eCollection 2016.
PMID: 27054364BACKGROUNDGuclu CY, Unver S, Aydinli B, Kazanci D, Dilber E, Ozgok A. The effect of sevoflurane vs. TIVA on cerebral oxygen saturation during cardiopulmonary bypass--randomized trial. Adv Clin Exp Med. 2014 Nov-Dec;23(6):919-24. doi: 10.17219/acem/37339.
PMID: 25618118BACKGROUND
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
October 30, 2017
First Posted
November 7, 2017
Study Start
December 31, 2016
Primary Completion
August 1, 2017
Study Completion
October 10, 2017
Last Updated
November 7, 2017
Record last verified: 2017-11