Medication Regimen Complexity and Glycemic Control in Patients With Diabetes

NCT03324971 | Completed

• 1 other identifier: KA-13071
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Polypharmacy is an alarming health issue that is defined as prescription of multiple medications, of which some are redundant or unnecessary. Due to comorbidities, diabetic patients are often prescribed multiple medications. Over prescribing occurs either due to, prescribing medications that are not indicated, continuation of certain medications beyond the time of indication, or prescribing more than one medication with the same effect. Improving glycaemic control is the cornerstone for the prevention and treatment of the diabetic complications.

Conditions

Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

• Change in Hemoglobin A1c

  measurement of hemoglobin A1c to determine glycemic control.

  3 months

Study Arms (1)

Diabetic patients with non-adherence and poly-pharmacy

EXPERIMENTAL

Medications review. Elimination of all unnecessary prescription to cut down the number of medications to the least possible number.

Other: Medications review

Interventions

Medications review OTHER

Medications review. Elimination of all unnecessary prescription to cut down the number of medications to the least possible number. This is in line with the best practice guidelines.

Diabetic patients with non-adherence and poly-pharmacy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All diabetic patients who are eligible by fulfilling all of the following criteria:
• HGBA1c ≥7 mg/dl.
• \) Poly-pharmacy: defined as the use of five or more medications.
• Non- compliance: patients were surveyed with both direct and indirect methods to identify non adherence.

Sponsors & Collaborators

• Kasr El Aini Hospital: lead

Study Sites (1)

Cairo university hospitals

Cairo, Egypt

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Tarek S Abdealziz

  Cairo University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior lecturer

Model Details: A prospective cohort study .The aim of this study to recruit a cohort of diabetic patients,eliminate unnecessary medications,aiming at improving adherence to anti-diabetic medications.

Study Record Dates

• First Submitted: October 20, 2017
• First Posted: October 30, 2017
• Study Start: June 2, 2017
• Primary Completion: October 2, 2017
• Study Completion: December 7, 2017
• Last Updated: September 5, 2018

Record last verified: 2018-08

Locations

EG (1)