Polymedication-Check With Insight in Patients' Medication Organisation and Comprehension of Generics

NCT03321058 | Completed

• 1 other identifier: PMC-Medication-Organisation
• Study Type: observational
• Target: 125
• Locations: 1 country
• Sites: 1

Brief Summary

Patients using multiple drugs including generics have found different solutions to manage their medication. During a Polymedication-Check (medication review type 2a service in community pharmacies) additional information about the organisation of patients' medication in daily life will be compiled in Swiss community pharmacies. Data will allow to better address patients' needs in their medication organisation and comprehension of generics.

Conditions

Medication Therapy Management; Medication Adherence

Keywords

Drug Substitution; Multicompartment Compliance Aid

Outcome Measures

Primary Outcomes (2)

• Insight in patients' organisation of polymedication

  Patients organise their multiple medications differently in daily life. The study will investigate the different organisation strategies to get a better understanding of patients' behaviour. The behaviour is assessed with a questionnaire containing 14 questions on the management of medication including single choice, multiple choice and free text questions. As example the number of patients already using a medication organisation system will be assessed, the number of patients using a weekly or daily pillbox will be assessed, and who is filling the medication organisation system.

  retrospective 3 months

• Insight in patients' comprehension of generics

  Patients have a different comprehension of generics including their advantages and disadvantages. The study will investigate patients' comprehension of generics to get a better understanding of patients' behaviour. The comprehension is assessed with a questionnaire containing 4 questions on the believes about generics including single choice, multiple choice and free text questions. As example the number of patients knowing that they use generics is assessed and the patient's personal opinion on advantages and disadvantages of generics is investigated.

  retrospective 3 months

Secondary Outcomes (4)

• Number of patients using Multicompartment Compliance Aids.

  retrospective 3 months

• Number of substitutable medicines.

  retrospective 3 months

• Swallowing difficulties

  retrospective 3 months

• Recommended use of Multicompartment Compliance Aids

  retrospective 3 months

Interventions

Assessment BEHAVIORAL

Assessment of patients' medication organisation and comprehension of generics

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study population comprises adults (18 years and older) with at least 4 prescribed medicines which they are taking for at least 3 months. One of those medicines must be a generic drug, one must be prescribed for a cardiovascular condition (ATC C01-10). Patients cannot have their medication provided in a Multicompartment Compliance Aid or a similar device by a specific service like home care, pharmacy or home for elderly.

You may qualify if:

• at least 4 medicines for at least 3 months
• at least 1 generic drug
• at least 1 medicine of ATC code cardiovascular system (C01-10)

You may not qualify if:

• medication provided in Multicompartment Compliance Aid or similar device by specific service (pharmacy, elderly home, home care)

Sponsors & Collaborators

• University Hospital, Basel, Switzerland: lead
• University of Basel: collaborator

Study Sites (1)

University of Basel

Basel, Canton of Basel-City, 4056, Switzerland

Location

Related Publications (4)

• Messerli M, Blozik E, Vriends N, Hersberger KE. Impact of a community pharmacist-led medication review on medicines use in patients on polypharmacy--a prospective randomised controlled trial. BMC Health Serv Res. 2016 Apr 23;16:145. doi: 10.1186/s12913-016-1384-8.

  PMID: 27108410 BACKGROUND

• Olsson E, Kalvemark Sporrong S. Pharmacists' experiences and attitudes regarding generic drugs and generic substitution: two sides of the coin. Int J Pharm Pract. 2012 Dec;20(6):377-83. doi: 10.1111/j.2042-7174.2012.00214.x. Epub 2012 Jun 1.

  PMID: 23134096 BACKGROUND

• Hakonsen H, Eilertsen M, Borge H, Toverud EL. Generic substitution: additional challenge for adherence in hypertensive patients? Curr Med Res Opin. 2009 Oct;25(10):2515-21. doi: 10.1185/03007990903192223.

  PMID: 19708764 BACKGROUND

• Nunney J, Raynor DK, Knapp P, Closs SJ. How do the attitudes and beliefs of older people and healthcare professionals impact on the use of multi-compartment compliance aids?: a qualitative study using grounded theory. Drugs Aging. 2011 May 1;28(5):403-14. doi: 10.2165/11587180-000000000-00000.

  PMID: 21542662 BACKGROUND

MeSH Terms

Conditions

Medication Adherence

Interventions

Restraint, Physical

Condition Hierarchy (Ancestors)

Patient Compliance; Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior

Intervention Hierarchy (Ancestors)

Behavior Control; Therapeutics; Immobilization; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof. Dr.

Study Record Dates

• First Submitted: June 1, 2017
• First Posted: October 25, 2017
• Study Start: January 6, 2017
• Primary Completion: October 1, 2017
• Study Completion: October 24, 2017
• Last Updated: October 25, 2017

Record last verified: 2017-10

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)