NCT03316287

Brief Summary

Hearing Loss (HL) affects over 5% of the world's population (WHO 2014) and is the 5th leading cause of Years Lived with Disability. HL is currently managed with Hearing Aids (HAs), i.e. programmable sound amplification devices that are worn by the hearing impaired subjects to address their hearing difficulties. HA use however is often problematic, costly and with poor overall benefits. The holistic management of HL requires appropriate public health policies for HL prevention, early diagnosis, long-term treatment and rehabilitation; detection and prevention of cognitive decline; and socioeconomic inclusion of HL patients. Currently the evidential basis for forming such policies is limited. The EVOTION project proposes to address this by collecting and analysing a big set of heterogeneous data, including HA usage, audiological, physiological, cognitive, clinical and medication, personal, behavioural, life style, occupational and environmental data. This will be done by: i. accessing big datasets of existing HA user data from the EVOTION clinical partners (UCL/UCLH and GST in the UK; OTICON in Denmark) ii. collection of prospective HA user data who will be recruited to the prospective EVOTION study and who will undergo some additional assessments iii. collection of real time dynamic data of the human participant HA users who will be given a smart phone with different apps (auditory tests; auditory training), sensors (recording of heart rate, blood pressure, respiratory rate etc.) and smart HAs (recording environmental factors such as noise levels, type of noise etc.) so that real life contextual factors that affect HA usage and outcome can be identified. These data will be analysed with big data analysis/data mining techniques in order to identify relationships between these in order to use this information to derive and support public health decisions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,080

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2018

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 10, 2017

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 20, 2017

Completed
4 months until next milestone

Study Start

First participant enrolled

March 1, 2018

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2018

Completed
Last Updated

March 26, 2020

Status Verified

March 1, 2020

Enrollment Period

9 months

First QC Date

October 10, 2017

Last Update Submit

March 25, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in "Glasgow Hearing Aid Benefit Profile" at 8 weeks

    Baseline (i.e. before the patient receives a hearing-aid) and at 8 weeks after receiving a hearing-aid

Study Arms (2)

Hearing aid + mobile phone

EXPERIMENTAL
Device: Hearing aidDevice: Mobile phone

Hearing aid + mobile phone + biosensor

EXPERIMENTAL
Device: Hearing aidDevice: Mobile phoneDevice: Sensor

Interventions

Smart hearing aid to allow collection of real time hearing aid usage data

Hearing aid + mobile phoneHearing aid + mobile phone + biosensor

Mobile phone linked with the hearing aids to allow users to change the device settings and perform additional listening tests

Hearing aid + mobile phoneHearing aid + mobile phone + biosensor
SensorDEVICE

Wearable biosensor for the collection of physiological data

Hearing aid + mobile phone + biosensor

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \>18 years
  • Basic understanding of oral and written English
  • Unilateral and/or bilateral mild to severe sensorineural hearing loss
  • Willing to use smart hearing aids for at least 2 hours daily on average
  • Willing/capable to use a mobile phone

You may not qualify if:

  • Dementia (MoCA\<22 )
  • Not agreeing or able to attend for f/u appointments
  • Not agreeing or able to use HA \>2 hours daily (average)
  • Not sufficient vision to use smartphone ap

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guy's and St. Thomas' Foundation Trust

London, United Kingdom

Location

Related Publications (1)

  • Dritsakis G, Kikidis D, Koloutsou N, Murdin L, Bibas A, Ploumidou K, Laplante-Levesque A, Pontoppidan NH, Bamiou DE. Clinical validation of a public health policy-making platform for hearing loss (EVOTION): protocol for a big data study. BMJ Open. 2018 Feb 15;8(2):e020978. doi: 10.1136/bmjopen-2017-020978.

MeSH Terms

Conditions

Hearing Loss

Interventions

Hearing AidsCalibration

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Wearable Electronic DevicesElectrical Equipment and SuppliesEquipment and SuppliesSensory AidsWeights and MeasuresInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 10, 2017

First Posted

October 20, 2017

Study Start

March 1, 2018

Primary Completion

November 30, 2018

Study Completion

November 30, 2018

Last Updated

March 26, 2020

Record last verified: 2020-03

Locations