Emergency Department Assessment of Right Ventricular Function and Size in the Post Cardiac Arrest Patient

NCT03309852 | Terminated DMC

• 1 other identifier: B2017:104
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

The right side of the heart of often overlooked in patients who are acutely unwell, as the main area of focus when performing echocardiography tends to be the left ventricle. The right ventricle can yield important diagnostic clues that can aid the clinician, particularly in cases where one may suspect elevated right sided pressures, such as those due to a pulmonary embolus. Although it is taught that a dilated right ventricle is associated in patients with pulmonary embolus, but in patients with spontaneous circulation. What is unknown is patients who sustain a cardiac arrest, does the same hold true. There is a paucity of literature surrounding the appearance of the right ventricle in the cardiac arrest patient acutely. This study aims to assess right ventricular size and function in the immediate post cardiac arrest phase.

Conditions

Right Ventricular Dysfunction; Cardiac Arrest

Outcome Measures

Primary Outcomes (1)

• Right ventricular dysfunction

  Assessment of RV dysfunction in post cardiac arrest patients.

  12 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Post cardiac arrest patients.

You may qualify if:

• Any post cardiac arrest patient who achieves return of spontaneous circulation that can have their RV assessed with point of care echo cardiography within 1 hour of ROSC.

You may not qualify if:

• Significant hemodynamic instability, pregnancy, incarcerated patients, age \<18.

Sponsors & Collaborators

• University of Manitoba: lead
• University of British Columbia: collaborator
• Queen's University, Kingston, Ontario: collaborator

Study Sites (1)

Health Sciences Centre

Winnipeg, Manitoba, R3A1R9, Canada

Location

MeSH Terms

Conditions

Ventricular Dysfunction, Right; Heart Arrest

Condition Hierarchy (Ancestors)

Ventricular Dysfunction; Heart Diseases; Cardiovascular Diseases

Study Officials

• Tomislav Jelic, MD

  University of Manitoba, Health Sciences Centre

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of Emergency Medicine

Study Record Dates

• First Submitted: October 10, 2017
• First Posted: October 16, 2017
• Study Start: October 6, 2017
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: August 24, 2025

Record last verified: 2025-08

Locations

CA (1)