NCT03306225

Brief Summary

The infectious endocarditis is a grave infection the incidence of which is at present esteemed at 30-100 episodes by million inhabitants a year. This infection is marked with a heavy morbi-mortality.Preliminary studies seem to show an abnormally high death rate at the patients presenting an infectious endocarditis to streptococci with an inhibitive minimal concentration raised to the amoxicilline. The aim of the study is to describe the epidemiology and the clinical presentations of the patients presenting an endocarditis to streptococci

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
414

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2016

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 8, 2016

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

October 5, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

October 10, 2017

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2018

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
Last Updated

February 5, 2020

Status Verified

January 1, 2020

Enrollment Period

2.5 years

First QC Date

October 5, 2017

Last Update Submit

February 3, 2020

Conditions

Endocarditis, Bacterial

Outcome Measures

Primary Outcomes (1)

  • Evaluation of factors associated to the mortality in the patients presenting an endocarditis to streptococci.

    an average of one year

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

all patient diagnostised for endocarditis between 2010 and 2015

You may qualify if:

  • age \> 18 years
  • endocartitis with steptococci with Duke's criteria

You may not qualify if:

  • age \< 18 years
  • suspiscious endocarditis without Duke's criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Groupe Hospitalier Paris Saint Joseph

Paris, Île-de-France Region, 75014, France

Location

MeSH Terms

Conditions

Endocarditis, Bacterial

Condition Hierarchy (Ancestors)

Bacterial InfectionsBacterial Infections and MycosesInfectionsCardiovascular InfectionsCardiovascular DiseasesEndocarditisHeart Diseases

Study Officials

  • PILMIS P Benoit, MD

    Fondation Hôpital Saint-Joseph

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 5, 2017

First Posted

October 10, 2017

Study Start

July 8, 2016

Primary Completion

December 31, 2018

Study Completion

December 31, 2019

Last Updated

February 5, 2020

Record last verified: 2020-01

Locations

FR(1)