NCT03304106

Brief Summary

Use of Artificial Intelligent (AI) technology to assist audiologists in programming cochlear implants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
102

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2017

Typical duration for not_applicable

Geographic Reach
1 country

9 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 3, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 6, 2017

Completed
13 days until next milestone

Study Start

First participant enrolled

October 19, 2017

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 18, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 18, 2019

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

October 29, 2020

Completed
Last Updated

October 29, 2020

Status Verified

October 1, 2020

Enrollment Period

1.9 years

First QC Date

October 3, 2017

Results QC Date

September 9, 2020

Last Update Submit

October 7, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in Monosyllabic Word Recognition Scores (CNC) in Quiet

    Monosyllabic word recognition was scored in quiet using Consonant-Nucleus-Consonant (CNC) words. Scores are listed as percentage correct thus a higher score (percentage) means a better outcome.Group 1: Preoperative to postoperative percentage performance after 6 months of cochlear implant use. Group 2: Visit A to Visit B after 1 month of cochlear implant use.

    Pre-operative/Visit A; Group 1: 6 months; Group 2: 1 month

Study Arms (2)

Newly Implanted CI Recipients

EXPERIMENTAL

Use of AI technology to assist in audiologist's evaluation and programming of new (standard of care-commercial) cochlear implant recipients

Device: Commercially available cochlear implant and AI system

Existing CI recipients

EXPERIMENTAL

Use of AI technology to assist in audiologist's evaluation and programming of existing cochlear implant recipients

Device: Commercially available cochlear implant and AI system

Interventions

Use of AI technology to assist in audiologist's evaluation and programming of cochlear implant recipients

Existing CI recipientsNewly Implanted CI Recipients

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Newly implanted and existing recipient Groups (Groups 1 and 2):
  • Age 12 and older
  • Monosyllabic word score administered at 60dBA (2 lists) with an appropriately fit hearing aid in the ear to be implanted who are receiving a cochlear implant as standard of care
  • Group 2: 3 months or greater combined experience with commercially available sound processors
  • Fluent spoken English skills

You may not qualify if:

  • Unrealistic expectations on the part of the subject regarding the possible benefits, risks, and limitations
  • Additional cognitive, medical or social handicaps that would prevent completion of all study requirements as determined by the Investigational team
  • Unwillingness or inability of the subject to comply with all investigational requirements
  • Use of an acoustic component in the implanted ear
  • Less than 18 active electrodes
  • Hybrid L Cochlear Implant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (9)

Rocky Mountain Ear Center

Englewood, Colorado, 80113, United States

Location

Greater Baltimore Medical Center

Baltimore, Maryland, 21204, United States

Location

University of Michigan

Ann Arbor, Michigan, 48108, United States

Location

Midwest Ear Institute

Kansas City, Missouri, 64111, United States

Location

New York University

New York, New York, 10016, United States

Location

Hearts for Hearing

Oklahoma City, Oklahoma, 73120, United States

Location

Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

Location

Cochlear Hearing Center Houston

Houston, Texas, 77074, United States

Location

Peak ENT Associates

Provo, Utah, 84604, United States

Location

Related Publications (1)

  • Zwolan TA, Presley R, Chenier L, Buck B. Investigation of an Outcomes-Driven, Computer-Assisted Approach to CI Fitting in Newly Implanted Patients. Ear Hear. 2021 May/Jun;42(3):558-564. doi: 10.1097/AUD.0000000000000957.

MeSH Terms

Conditions

Hearing Loss, Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Laura Chenier, Clinical Project Manager
Organization
Cochlear Limited

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 3, 2017

First Posted

October 6, 2017

Study Start

October 19, 2017

Primary Completion

September 18, 2019

Study Completion

September 18, 2019

Last Updated

October 29, 2020

Results First Posted

October 29, 2020

Record last verified: 2020-10

Locations