NCT03300895

Brief Summary

High-intensity interval training (HIIT) is currently considered one of the most effective strategies to improved cardiorespiratory fitness, which is recognized as a protective factor for cardiovascular diseases and metabolic diseases such as overweight and obesity. However, current evidence is still limited and requires clarity (frequency, time per session and intensity) regarding to greater increases attributed to HIIT. The aim of this study is to compare the effect of a low-volume high-intensity interval training versus a moderate-intensity continuous exercise on maximal oxygen consumption in overweight women 18 to 44 years old.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable healthy-volunteers

Timeline
Completed

Started Aug 2017

Typical duration for not_applicable healthy-volunteers

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 14, 2017

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 28, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 4, 2017

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2018

Completed
Last Updated

February 4, 2019

Status Verified

February 1, 2019

Enrollment Period

1.3 years

First QC Date

September 28, 2017

Last Update Submit

February 1, 2019

Conditions

Healthy Volunteers

Outcome Measures

Primary Outcomes (1)

  • Change in maximal oxygen consumption

    Maximal oxygen consumption will be obtained using a graded exercise test on a treadmill (Trackmaster® model TMX 425C) using a portable K4b2 gas analyzer (Cosmed Inc., IL, USA)

    Baseline and after 10 weeks

Secondary Outcomes (1)

  • Change in total body fat

    Baseline and after 10 weeks

Study Arms (2)

High-intensity interval training

EXPERIMENTAL
Other: High-intensity interval training

Moderate-intensity continuous exercise

ACTIVE COMPARATOR
Other: Comparator: Moderate-intensity continuous exercise

Interventions

High-intensity interval trainingOTHER

21.5 minutes of high-intensity interval exercise at an intensity between 90-95 of HRmax (15x30 s), with recoveries at 50-60% of HRmax (14x60 s). 24 sessions, 3x weekly of walking and running outdoors on a sports field in a supervised manner.

High-intensity interval training
Comparator: Moderate-intensity continuous exerciseOTHER

30 minutes of continuous exercise at an intensity between 65-75% of HRmax. 24 sessions, 3x weekly of walking and jogging outdoors on a sports field in a supervised manner

Moderate-intensity continuous exercise

Eligibility Criteria

Age18 Years - 44 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Overweight (≥ 25 kg/m-2) women 18 to 44 years.
  • Healthy volunteers.
  • Perform ≤ 600 Met/min/week.

You may not qualify if:

  • Perform high-intensity interval exercise in the last six month.
  • Smoker.
  • History of asthma.
  • History of diabetes.
  • History of hypertension.
  • History of cardiovascular disease.
  • History of coronary heart disease.
  • Arrhythmias.
  • Personal history of surgical procedures in the last three months
  • Uncontrolled non-communicable diseases
  • Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids.
  • Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
  • Psychoactive drug abuse.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad de Antioquia

Medellín, Antioquia, Colombia

Location

Related Publications (1)

  • Arboleda-Serna VH, Patino-Villada FA, Pinzon-Castro DA, Arango-Velez EF. Effects of low-volume, high-intensity interval training on maximal oxygen consumption, body fat percentage and health-related quality of life in women with overweight: A randomized controlled trial. J Exerc Sci Fit. 2022 Apr;20(2):108-112. doi: 10.1016/j.jesf.2022.01.004. Epub 2022 Feb 4.

    PMID: 35228846DERIVED

MeSH Terms

Interventions

High-Intensity Interval Training

Intervention Hierarchy (Ancestors)

Physical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD, MSc

Study Record Dates

First Submitted

September 28, 2017

First Posted

October 4, 2017

Study Start

August 14, 2017

Primary Completion

November 30, 2018

Study Completion

November 30, 2018

Last Updated

February 4, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations

CO(1)