Brief New Treatment for Suicide Attempts

NCT03300596 | Completed

• 1 other identifier: RSRB00069554
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Individuals with alcohol or drug use problems who are hospitalized for suicide attempt are at high risk for reattempt. This treatment development study adapts a promising outpatient intervention to prevent suicide reattempt in order to administer it during hospitalization to individuals with alcohol and drug use problems, and to test the adapted intervention in a pilot randomized controlled trial.

Conditions

Suicide, Attempted; Drug Use; Alcohol; Use, Problem

Outcome Measures

Primary Outcomes (1)

• suicide reattempt

  number who reattempt suicide

  6 months

Study Arms (2)

brief intervention to prevent suicide attempt

EXPERIMENTAL

Individuals presenting to hospital following a suicide attempt who are age 18-plus and screen positive for alcohol or drug use problem

Behavioral: Brief intervention to prevent suicide attempt

standard of care

OTHER

Individuals presenting to hospital following a suicide attempt who are age 18-plus and screen positive for alcohol or drug use problem

Behavioral: Enhanced treatment as usual

Interventions

Brief intervention to prevent suicide attempt BEHAVIORAL

A patient-centered, 3-session intervention that calls for videotaping the narrative story of a patient's suicide attempt, in his/her own words (session 1); reviewing segments of the tape to arrive at a shared understanding of the attempt and the sequence of events that led to it (session 2); and using this information, along with a homework task completed by the patient in-between sessions, in order to develop a collaborative, comprehensive written safety plan that addresses the patient's unique vulnerabilities (session 3).

Also known as: Modification of the Attempted Suicide Short Intervention Program (ASSIP)

brief intervention to prevent suicide attempt

Enhanced treatment as usual BEHAVIORAL

Safety procedures' control intervention. For these procedures we will share summary results of the research assessments regarding suicidal thoughts, suicidal behaviors, alcohol and drug use and related problems, and depressive symptoms with appropriate hospital clinical staff. We will also arrange to send this information, with participants' permission, to their ongoing therapist or treatment program and, if none exists, to the therapist or program to which they are being referred. In this regard, the research assessment protocol serves a dual function of helping with additional monitoring of high-risk patients in addition to providing data for the study.

standard of care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• suicide attempt within one week of hospitalization with acknowledgment of some intent to die using a standard item
• problematic alcohol or drug use as determined by score \>8 on Alcohol Use Disorders Identification Test, AUDIT or \>3 on the 10-item version of the Drug Abuse Screening Test, DAST-10
• admission to hospital
• residence within 40 miles of Strong Memorial Hospital

You may not qualify if:

• under age 18
• treated in ED, CPEP, or observation unit only
• unable to communicate with the researcher in English
• unable to comprehend the nature of the study
• participation untenable from a medical (e.g., intubated), psychiatric (e.g., florid psychosis), or behavioral (e.g., refusing to speak with staff) standpoint
• short hospital length of stay, ruling out administering three sessions of the therapy prior to discharge

Sponsors & Collaborators

• University of Rochester: lead
• National Institute on Alcohol Abuse and Alcoholism (NIAAA): collaborator

Study Sites (1)

University of Rochester Medical Center

Rochester, New York, 14642, United States

Location

Related Publications (3)

• Conner KR, Kearns JC, Denneson LM. Qualitative analysis of hospital patient narratives of warning signs on the day of their suicide attempt. Gen Hosp Psychiatry. 2022 Nov-Dec;79:146-151. doi: 10.1016/j.genhosppsych.2022.11.001. Epub 2022 Nov 9.

  PMID: 36375343 DERIVED

• Conner KR, Kearns JC, Esposito EC, Pizzarello E, Wiegand TJ, Britton PC, Michel K, Gysin-Maillart AC, Goldston DB. Pilot RCT of the Attempted Suicide Short Intervention Program (ASSIP) adapted for rapid delivery during hospitalization to adult suicide attempt patients with substance use problems. Gen Hosp Psychiatry. 2021 Sep-Oct;72:66-72. doi: 10.1016/j.genhosppsych.2021.07.002. Epub 2021 Jul 19.

  PMID: 34304029 DERIVED

• Witt KG, Hetrick SE, Rajaram G, Hazell P, Taylor Salisbury TL, Townsend E, Hawton K. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev. 2021 Apr 22;4(4):CD013668. doi: 10.1002/14651858.CD013668.pub2.

  PMID: 33884617 DERIVED

MeSH Terms

Conditions

Suicide, Attempted; Alcoholism

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior; Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 28, 2017
• First Posted: October 3, 2017
• Study Start: March 12, 2018
• Primary Completion: September 15, 2020
• Study Completion: September 15, 2020
• Last Updated: September 17, 2020

Record last verified: 2020-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)