Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment
One Year Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment-A Prospective,Multicenter,Cohort Study
1 other identifier
observational
12,043
1 country
19
Brief Summary
The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort，and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2017
Typical duration for all trials
19 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 26, 2017
CompletedFirst Posted
Study publicly available on registry
September 29, 2017
CompletedStudy Start
First participant enrolled
December 21, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 4, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2021
CompletedOctober 1, 2021
September 1, 2021
3 years
September 26, 2017
September 29, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
incidence rate of heart failure
incidence rate of heart failure of acute myocardial infarction at 12th month
12th month after diacharge
Secondary Outcomes (3)
MACCE rate
12th month after diacharge
bleeding rate
12th month after diacharge
severe adverse drug reactions
12th month after diacharge
Study Arms (2)
optimized group
the patients in this group have been given the suggestive treatment from guideline.
un-optimized group
the patients in this group have not been given the suggestive treatment from guideline.
Eligibility Criteria
acute myocadial infarction
You may qualify if:
- age≥18 years
- diagnosed acute myocardial infarction
- signed the informed consent form
You may not qualify if:
- AMI is caused by surgery, trauma, gastrointestinal bleeding or complications of PCI;
- AMI occurred in patients who have been hospitalized for other reasons;
- patients with previous history of chronic heart failure;
- researchers judging that patient's compliance was poor and could not complete the study according to the requirements.
- life expectancy is less than 12 months;
- heart transplant patients;
- patients with tumors;
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (19)
Beijing An Zhen Hospital, Capital Medical University
Beijing, Beijing Municipality, 100029, China
Peking Univerisity People'Hospital
Beijing, Beijing Municipality, 100044, China
Beijing Chao-Yang Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Peking University First Hospital
Beijing, Beijing Municipality, China
Guangdong general hospital
Guangzhou, Guangdong, China
The first affiliated hospital of Guangxi medical university
Nanning, Guangxi, 530021, China
Second hospital of hebei medical university
Shijiazhuang, Hebei, China
Daqing Oilfield General Hospital
Daqing, Heilongjiang, 163001, China
The first affiliated hospital of Zhengzhou medical university
Zhengzhou, Henan, China
Zhongda Hospital Southeast University
Nanjing, Jiangsu, 210009, China
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330006, China
The Second Hospital of Jilin University
Changchun, Jilin, 130000, China
the second affiliated hospital of Dalian medical university
Dalian, Liaoning, China
Shenyang military district general hospital of the people's liberation army
Shenyang, Liaoning, China
The first affiliated hospital of military medical university
Xi’an, Shanxi, China
Third Military Medical University
Chongqing, Sichuan, China
The General Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China
Tianjin Chest Hospital
Tianjin, Tianjin Municipality, China
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, China
Related Publications (4)
Wang J, Li Z, Yang G, Fang C, Yin Y, Zheng Z, Wang H, Fang S, Dai J, Wang S, Yang S, Yu B. Pseudo-targeted metabolic profile differences between emergency patients with type 1 and type 2 myocardial infarction diagnosed by optical coherence tomography. Clin Chim Acta. 2024 Feb 1;554:117745. doi: 10.1016/j.cca.2023.117745. Epub 2024 Jan 6.
PMID: 38185283DERIVEDLang X, Zhao B, Fang S, Li L, Li Z, Wu N, Zhang Y, Xing L, Li Y, Zhang Y. Higher Peripheral Thyroid Sensitivity Is Linked to a Lower Risk of Heart Failure After Acute Myocardial Infarction. J Clin Endocrinol Metab. 2023 Oct 18;108(11):2950-2960. doi: 10.1210/clinem/dgad240.
PMID: 37104944DERIVEDZeng M, Zhao C, Bao X, Liu M, He L, Xu Y, Meng W, Qin Y, Weng Z, Yi B, Zhang D, Wang S, Luo X, Lv Y, Chen X, Sun Q, Feng X, Gao Z, Sun Y, Demuyakor A, Li J, Hu S, Guagliumi G, Mintz GS, Jia H, Yu B. Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT. JACC Cardiovasc Imaging. 2023 Apr;16(4):521-532. doi: 10.1016/j.jcmg.2022.10.023. Epub 2022 Dec 14.
PMID: 36648054DERIVEDLi L, Zhang X, Wang Y, Yu X, Jia H, Hou J, Li C, Zhang W, Yang W, Liu B, Lu L, Tan N, Yu B, Li K. A Novel Risk Score to Predict In-Hospital Mortality in Patients With Acute Myocardial Infarction: Results From a Prospective Observational Cohort. Front Cardiovasc Med. 2022 Apr 7;9:840485. doi: 10.3389/fcvm.2022.840485. eCollection 2022.
PMID: 35463775DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- director
Study Record Dates
First Submitted
September 26, 2017
First Posted
September 29, 2017
Study Start
December 21, 2017
Primary Completion
December 4, 2020
Study Completion
June 30, 2021
Last Updated
October 1, 2021
Record last verified: 2021-09
Data Sharing
- IPD Sharing
- Will not share