Metabolomic Study in Huntington's Disease (METABO-HD)
1 other identifier
interventional
150
1 country
1
Brief Summary
The purpose of this project is to study Huntington's disease by metabolomic approach.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 15, 2017
CompletedFirst Posted
Study publicly available on registry
September 28, 2017
CompletedStudy Start
First participant enrolled
October 9, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2019
CompletedNovember 1, 2017
September 1, 2017
1.9 years
September 15, 2017
October 30, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
metabolite mass
by chromatography and mass spectrometry
at baseline
Study Arms (3)
presymptomatic
EXPERIMENTALsymptomatic
EXPERIMENTALcontrols
OTHERInterventions
Eligibility Criteria
You may qualify if:
- For all groups:
- age between 20 and 70 years
- signature of the informed consent
- covered by social security
- For presymptomatic group:
- positive genetic test with CAG repeat length ≥ 37 in HTT gene
- Unified Huntington Disease Rating Scale ≤ 5
- For symptomatic group:
- positive genetic test with CAG repeat length ≥ 37 in HTT gene
- The Unified Huntington's Disease Rating Scale motor score ≥ 6
- The Total Functional Capacity score ≥ 11
You may not qualify if:
- pregnancy and breastfeeding
- persons deprived of their liberty by judicial or administrative decision
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU Angers
Angers, 49000, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Christophe Verny, PU-PH
University Hospital, Angers
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 15, 2017
First Posted
September 28, 2017
Study Start
October 9, 2017
Primary Completion
September 1, 2019
Study Completion
September 1, 2019
Last Updated
November 1, 2017
Record last verified: 2017-09