Trials Sponsors Conditions Drugs Pricing

Conditions

Obsessive-compulsive Disorders and Symptoms

Keywords

Transcranial Direct Current StimulationSupplementary motor areaOrbitofrontal cortex

Outcome Measures

Primary Outcomes (1)

The primary outcome measure is used to show that bifocal tDCS with anodal stimulation on OFC and cathodic stimulation on the SMA is an effective treatment
Score improvement on the Y-BOCS after 14 days compared to the baseline
Day 14

Secondary Outcomes (11)

Evaluate the persistence of therapeutic response at 45 days
Day 45
Evaluate the persistence of therapeutic response at 105 days
Day 105
Evaluate the therapeutic effect of tDCS on the depressive and anxious symptoms associated with Obsessive compulsive disorder at 14 days
Day 14
Evaluate the therapeutic effect of tDCS on the depressive and anxious symptoms associated with Obsessive compulsive disorder at 45 days
Day 45
Evaluate the therapeutic effect of tDCS on the depressive and anxious symptoms associated with Obsessive compulsive disorder at 105 days
Day 105
+6 more secondary outcomes

Study Arms (1)

bifocal stimulation

EXPERIMENTAL

Transcranial direct current Bifocal stimulation

Other: bifocal stimulation with tDCS

Interventions

bifocal stimulation with tDCSOther

Patients will receive an active Treatment with tDCS (10 sessions of 30 mn with an intensity of 2 mA)

bifocal stimulation

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 70 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Meets criteria for obsessive compulsive disorder according to DSM-IV with a "good insight" (BABS),
Age: Participants will be both males and females, 18-70 years of age included.

Sponsors & Collaborators

Centre Hospitalier Henri Laborit
Otherlead

Study Sites (1)

Centre Hospitalier Henri Laborit

Poitiers, 86021, France

Related Publications (1)

Harika-Germaneau G, Heit D, Chatard A, Thirioux B, Langbour N, Jaafari N. Treating refractory obsessive-compulsive disorder with transcranial direct current stimulation: An open label study. Brain Behav. 2020 Jul;10(7):e01648. doi: 10.1002/brb3.1648. Epub 2020 May 14.
PMID: 32406608RESULT

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Interventions

Transcranial Direct Current Stimulation

Condition Hierarchy (Ancestors)

Anxiety DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsConvulsive TherapyPsychiatric Somatic TherapiesBehavioral Disciplines and ActivitiesElectroshockPsychological Techniques

Study Officials

Nematollah JAAFARI, Professor
Centre Hospitalier Henri Laborit
STUDY DIRECTOR

Enrollment

20 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: not applicable
Allocation: NA
Masking: NONE
Purpose: TREATMENT
Intervention Model: SINGLE GROUP
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

September 7, 2017

First Posted

September 15, 2017

Study Start

February 19, 2016

Actual (reported)

tDCS Stimulation to Treat Patients With Severe and Resistant Obsessive Compulsive Disorder-Pilot Study

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (11)

Study Arms (1)

bifocal stimulation

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (11)

Study Arms (1)

bifocal stimulation

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations