Sample Collection and Tracking for the Developmental Therapeutics Clinic

NCT03269578 | Recruiting

• 2 other identifiers: 17015617-C-0156
• Study Type: observational
• Target: 3,000
• Locations: 1 country
• Sites: 1

Brief Summary

Background: People who join a study in the Developmental Therapeutics Clinic (DTC) have tests. These include blood draws and biopsies. Researchers collect data from these samples. Some people take part in more than one study at the DTC. At this time, data are connected only with one single study. Researchers want to access people s medical records. This will allow them to link the research data from all their studies they have or will take part in. Researchers also want to collect medical data about their diagnosis and treatment history. This will allow them to see how their cancer reacted to different drugs over time. Objective: To enter people into a master protocol to connect research sample and treatment data across DTC studies. Eligibility: People ages 18 and older who are being evaluated or treated for cancer in the DTC Design: Participants will allow researchers to look at all the data from their research samples. This includes those from their current, past, and any future NIH studies. Participants will allow researchers to access some of their medical data. This includes age, diagnosis, treatment history, and response to treatment. Participants will provide no new samples. ...

Conditions

Neoplasms; Lymphoma

Keywords

Pharmacodynamics; Tissue Collection; Tissue Biopsies; Biospecimen; Assay Development; Natural History

Outcome Measures

Primary Outcomes (1)

• Obtaining informed consent

  Collation of research sample and treatment data from individual patients across their participation in consecutive DTC clinical trials

  Time of enrollment

Study Arms (1)

1

Patients with cancer or benign tumors being treated on NCI/DTC studies

Eligibility Criteria

• Age: 18 Years - 120 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients on research protocols at the Developmental Therapeutics Clinic

You may qualify if:

• Patients who are being evaluated and/or treated for cancer or benign tuumors in the Developmental Therapeutics Clinic at the NIH Clinical Center
• Ability to understand and willingness to sign a written informed consent document indicating their willingness to have data from their tissue or biologic fluid research specimens and limited medial information used for research as outlined in this protocol and to allow protocol staff access to the CRIS database and their Medical Records Number (MRN).
• Age greater than or equal to 18 years
• ECLUSION CRITERIA:
• None

Sponsors & Collaborators

• National Cancer Institute (NCI): lead

Study Sites (1)

National Institutes of Health Clinical Center

Bethesda, Maryland, 20892, United States

RECRUITING

Related Links

• NIH Clinical Center Detailed Web Page

MeSH Terms

Conditions

Neoplasms; Lymphoma

Condition Hierarchy (Ancestors)

Neoplasms by Histologic Type; Lymphoproliferative Disorders; Lymphatic Diseases; Hemic and Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases

Study Officials

• Alice P Chen, M.D.

  National Cancer Institute (NCI)

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jennifer H Zlott

CONTACT

(240) 760-6046; zlottjh@mail.nih.gov

Alice P Chen, M.D.

CONTACT

(240) 781-3320; chenali@mail.nih.gov

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 31, 2017
• First Posted: September 1, 2017
• Study Start: August 28, 2017
• Primary Completion (Estimated): May 23, 2027
• Study Completion (Estimated): May 30, 2027
• Last Updated: April 24, 2026

Record last verified: 2025-06-27

Locations

US (1)