NCT03268863

Brief Summary

This study is testing whether or not low-cost, virtual reality (VR) headsets for mobile phones can be used as a potential distractor from pain and thus would have clinical applications as a low-cost, non-pharmaceutical method to increase pain tolerance in patients undergoing painful or uncomfortable procedures. To do this, the investigators are asking volunteers to submerge their hand up to the wrist in cold water (Cold Pressor Test), either while playing an interactive virtual reality game on the headset, or while wearing a VR headset that is turned off as a control. The investigators will record the participants' tolerance to cold water as measured by how long the participants are able to keep their hand in the cold water.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable pain

Timeline
Completed

Started Sep 2017

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 28, 2017

Completed
1 month until next milestone

First Posted

Study publicly available on registry

August 31, 2017

Completed
10 days until next milestone

Study Start

First participant enrolled

September 10, 2017

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 10, 2018

Completed
10 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2018

Completed
Last Updated

June 11, 2019

Status Verified

June 1, 2019

Enrollment Period

10 months

First QC Date

July 28, 2017

Last Update Submit

June 7, 2019

Conditions

Keywords

pain toleranceperioperative painvirtual reality therapy

Outcome Measures

Primary Outcomes (1)

  • Pain Tolerance

    Likert Scale, 0-10

    10 minutes

Secondary Outcomes (3)

  • Pain threshold

    10 minutes

  • maximal pain

    10 minutes

  • Nausea

    10 minutes

Study Arms (2)

Virtual Reality

EXPERIMENTAL

Google Cardboard Virtual Reality headset running an interactive game

Device: Virtual RealityOther: Cold Pressor

Control

SHAM COMPARATOR

Powered down Google Cardboard Virtual Reality headset

Other: Cold Pressor

Interventions

Google Cardboard virtual reality headset

Virtual Reality

A cold ice water bath for use in pain/discomfort simulation

Also known as: Cold Pressor Test
ControlVirtual Reality

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Healthy adult Mayo Clinic students and employees

You may not qualify if:

  • Participants who are known to be sensitive to VR technology and/or have undesirable reactions to VR technology (i.e. dizziness, motion sickness)
  • Participants with significant alcohol/smoking histories, sickle cell anemia, history of previous myocardial infarction and/or coronary artery disease, malignant hypertension, metabolic
  • dysfunctions, pregnancy, Raynaud's disease, epilepsy, severe mental disorders, chronic pain conditions, or diseases producing neuropathic pain
  • Participants that have used drugs/alcohol the day prior to the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Mayo Clinic in Arizona

Scottsdale, Arizona, 85259, United States

Location

Mayo Clinic in Rochester

Rochester, Minnesota, 55901, United States

Location

Related Links

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Janet Vittone

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Consultant, General Internal Medicine

Study Record Dates

First Submitted

July 28, 2017

First Posted

August 31, 2017

Study Start

September 10, 2017

Primary Completion

July 10, 2018

Study Completion

July 20, 2018

Last Updated

June 11, 2019

Record last verified: 2019-06

Data Sharing

IPD Sharing
Will not share

Locations