Incidence of Renal Tubular Acidosis in Nephrology Unit in Assiut University Childern Hospital

NCT03268460 | Unknown

• 1 other identifier: RTA in childern
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Providing summarized information on the clinical and biochemical characteristics and types of renal tubular acidosis in children in Assiut University Childern Hospital.

Conditions

Renal Tubule Acidosis

Outcome Measures

Primary Outcomes (1)

• percentage of cases with newly diagnosed renal tubular acidosis

  percentage of cases presented by metabolic acidosis , failure to thrive and polyuria and diagnosed as RTA by arterial blood gases, blood anion gap, serum electrolytes, kidney function tests and urine analysis.

  Baseline

Secondary Outcomes (1)

• percentage of cases with each type of RTA

  Baseline

Interventions

Arterial blood gases DIAGNOSTIC_TEST

blood PH, HCO3

Blood anion gap DIAGNOSTIC_TEST

(Na+) - (Cl- + HCO3-)

serum electrolytes DIAGNOSTIC_TEST

Na+ , K+ , Cl- and calcium

renal function test DIAGNOSTIC_TEST

blood urea and serum creatinine

urine analysis DIAGNOSTIC_TEST

urine PH, specific gravity, aminoaciduria, glycosuria, phospaturia and 24 hr urine calcium

Eligibility Criteria

• Age: 1 Year - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

• All cases presented with hypokalemia and normal anion gap hyperchloremic metabolic acidosis with a relatively normal glomerular filteration rate.

You may qualify if:

• Age : From 1 year to 18 year.
• Sex : Both sex male and female.
• All cases presented with hypokalemia and normal anion gap hyperchloremic metabolic acidosis with a relatively normal glomerular filteration rate.

You may not qualify if:

• Acute diarrhea .
• Urinary diversions.
• Post hypocapnia.
• Postobstructive diuresis.
• Interstitial nephritis.
• Active urinary tract infection.
• Intake of medications interfere with urinary acidification.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Acidosis, Renal Tubular

Interventions

Blood Gas Analysis; Acid-Base Equilibrium; Kidney Function Tests; Urinalysis

Condition Hierarchy (Ancestors)

Renal Tubular Transport, Inborn Errors; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Acidosis; Acid-Base Imbalance; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Blood Chemical Analysis; Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Respiratory Function Tests; Diagnostic Techniques, Respiratory System; Investigative Techniques; Biochemical Phenomena; Chemical Phenomena; Hydrogen-Ion Concentration; Metabolism; Homeostasis; Physiological Phenomena; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena; Diagnostic Techniques, Urological

Central Study Contacts

Sally Ezzat

CONTACT

01001349860; sallyezzat1992@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: August 28, 2017
• First Posted: August 31, 2017
• Study Start: January 1, 2018
• Primary Completion: January 1, 2019
• Study Completion: January 1, 2019
• Last Updated: September 1, 2017

Record last verified: 2017-08