Drug Abuse Among Elective Surgeries: an Observational Study.

NCT05123521 | Completed DMC

• 1 other identifier: amera master
• Study Type: observational
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

Drug abusers and addicts form a challenge to the anesthetist because of the added potential risks involved in the administration of anesthesia to this subset of patients, including potential unforeseen drug-drug interactions. In this study, we aimed at screening all patients scheduled for elective orthopedic or general surgeries at the Cairo University Teaching Hospital during a set period of time for the most commonly abused drugs in Egypt.

Conditions

Drug Abuse

Keywords

drug abuse; Cairo Teaching Hospital; elective surgery

Outcome Measures

Primary Outcomes (1)

• urine analysis

  multi-drug screen panel dip steak (Abon Biopharm (Hangzhou) , Ltd)

  THREE MONTHS

Interventions

urine analysis DIAGNOSTIC_TEST

Urine was then tested for evidence of substance abuse using the multi-drug screen panel dip steak ABONtm (Abon Biopharm (Hangzhou) CO., Ltd) which is a lateral flow chromatographic immunoassay . It allowed for qualitative detection of multiple drugs in a single run. This kit was chosen for its ability to detect the most commonly abused substances in Egypt, namely: opioids, benzodiazepines, hashish, and tramadol. A single coloured line at region C for of a specific drug indicated a positive result, whilst two coloured lines at both regions C and T indicated a negative result. The absence of coloured lines was an indication of the invalidity of the particular kit, and the kit was discarded.

Eligibility Criteria

• Age: 15 Years - 60 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

those who had presented to the General Surgery or Orthopaedics Departments

You may qualify if:

• male or female patients classified as American Society of Anaesthesiology (ASA) I or II patients
• patients between 15 and 60 years of age
• patients scheduled for elective surgery.

You may not qualify if:

• emergency surgery
• those with disturbed conscious levels
• history of psychological illness
• who refused to give consent

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Giza Governorate, 1234, Egypt

Location

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Urinalysis

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Clinical Chemistry Tests; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Diagnostic Techniques, Urological; Investigative Techniques

Study Officials

• Hassan Ali, Md

  Cairo University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate prof

Study Record Dates

• First Submitted: October 23, 2021
• First Posted: November 17, 2021
• Study Start: August 1, 2018
• Primary Completion: January 28, 2019
• Study Completion: February 28, 2019
• Last Updated: November 17, 2021

Record last verified: 2021-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)