Investigation of Relationship Between Contrast Nephropathy and Caval Index Measurement in Patients With Ileus in ED

NCT03261518 | Unknown

• 1 other identifier: KÜ GOKAEK 2017/1.13
• Study Type: observational
• Target: 250
• Locations: 0 countries
• Sites: N/A

Brief Summary

In this study, the investigators aimed to evaluate the incidence of vena cava inferior diamater on ultrasound guidance of intravascular volume before diagnosis of contrast \- enhanced CT for diagnostic purposes in ileus patients and to investigate the incidence and risk of developing contrast nephropathy due to contrast - enhanced CT.

Conditions

Ileus; Mechanical; Contrast-induced Nephropathy

Keywords

ileus; Contrast-induced Nephropathy; vena cava inferior

Outcome Measures

Primary Outcomes (1)

• Estimate contrast nephropathy in patients with low volume status by calculating Vena cava index

  Estimate contrast nephropathy in patients with low volume status by calculating Vena cava index In this study, we aimed to evaluate the incidence of vena cava inferior vena cava on ultrasound guidance of intravascular volume before diagnosis of contrast-enhanced CT and to investigate the incidence and development of contrast nephropathy due to contrast-enhanced CT.

  48 hours

Interventions

inferior vena cava ultrasound PROCEDURE

Place the patient in the supine position. The degree of elevation of the head of the bed has not been shown to make a significant difference in measurements. The diameter of the IVC for calculation of the caval index should be measured 2 cm from where it enters the right atrium .An alternative way to visualize respiratory variation is to use M-mode, with the beam overlying the IVC 2 cm from the right atrium.The inspiratory and expiratory diameter can then be measured on the M-mode image, at the smallest and largest locations, respectively.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Community sample

You may qualify if:

• Patients who underwent contrast abdominal CT and were admitted to our general surgery department for at least 48 hours
• Written informed patients
• Patients older than 18 years

You may not qualify if:

• With contrast agent allergy
• Story of renal replacement therapy
• Contrast agent exposure within the last 10 days
• Pregnancy

Sponsors & Collaborators

• Derince Training and Research Hospital: lead

Related Publications (4)

• Habeb M, Agac MT, Aliyev F, Pehlivanoglu S, Ongen Z. [Contrast media-induced nephropathy: clinical burden and current attempts for prevention]. Anadolu Kardiyol Derg. 2005 Jun;5(2):124-9. Turkish.

  PMID: 15939688 BACKGROUND

• McCullough PA, Choi JP, Feghali GA, Schussler JM, Stoler RM, Vallabahn RC, Mehta A. Contrast-Induced Acute Kidney Injury. J Am Coll Cardiol. 2016 Sep 27;68(13):1465-1473. doi: 10.1016/j.jacc.2016.05.099.

  PMID: 27659469 BACKGROUND

• Sanaei-Ardekani M, Movahed MR, Movafagh S, Ghahramani N. Contrast-induced nephropathy: a review. Cardiovasc Revasc Med. 2005 Apr-Jun;6(2):82-8. doi: 10.1016/j.carrev.2005.07.004.

  PMID: 16263365 BACKGROUND

• Kelly AM, Dwamena B, Cronin P, Bernstein SJ, Carlos RC. Meta-analysis: effectiveness of drugs for preventing contrast-induced nephropathy. Ann Intern Med. 2008 Feb 19;148(4):284-94. doi: 10.7326/0003-4819-148-4-200802190-00007.

  PMID: 18283206 BACKGROUND

MeSH Terms

Conditions

Ileus

Condition Hierarchy (Ancestors)

Intestinal Obstruction; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases

Central Study Contacts

ALI Y UYANIK, RESIDENT

CONTACT

+90 505 220 84 09; alifen_56@hotmail.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: EMERGENCY MEDICINE RESIDENT

Study Record Dates

• First Submitted: August 23, 2017
• First Posted: August 25, 2017
• Study Start: August 24, 2017
• Primary Completion: December 15, 2017
• Study Completion: December 15, 2017
• Last Updated: August 25, 2017

Record last verified: 2017-08