Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention

NCT03266458 | Unknown

• 1 other identifier: 17100308
• Study Type: observational
• Target: 210
• Locations: 1 country
• Sites: 1

Brief Summary

all patient presented with ST elevated myocardial infarction and underwent PPCI will be calculated with CHA2DS2-VASC score and contrast volume / creatinine clearance as apredictive value for Contrast induced nephropathy and the predictive value of these scores will be compared with the approved predictive value of MEHRAN score which is also will be calculated to every patient .

Conditions

Contrast-induced Nephropathy

Outcome Measures

Primary Outcomes (1)

• Contrast induced nephropathy

  contrast induced nephropathy (CIN) defined as an increase in serum creatinine ≥25% or ≥0.5 mg/dl from baseline within 48 h after contrast exposure so we will follow up creatinine level according to the defenition .

  48 hours

Interventions

Primary percutaneous coronary intervention PROCEDURE

Urgent percutaneous coronary intervention for ST- elevation myocardial infarction patients.

Also known as: PPCI

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The study will include \> 210 patients ( calculated sample size) who have STEMI and undergoing PPCI in Cath lab of Orman university Heart Hospital of Assiut University starting from January 2018 .

You may qualify if:

• All patients with STEMI who are eligible for primary PCI will be enrolled in the study.

You may not qualify if:

• (1) If the coronary anatomy was not suitable for PCI. (2) If emergency bypass grafting was required. (3) Patients in chronic peritoneal or hemodialytic treatment.

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Assiut University Hospitals

Asyut, Egypt

Location

Related Publications (33)

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Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 2 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at cardiology department at assiut university hospital

Study Record Dates

• First Submitted: August 25, 2017
• First Posted: August 30, 2017
• Study Start: January 1, 2018
• Primary Completion: November 30, 2018
• Study Completion: December 30, 2018
• Last Updated: August 30, 2017

Record last verified: 2017-08

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)