NCT03254472

Brief Summary

The investigators conducted a retrospective analysis of all measured concentrations performed in a large subset of laboratories located in the French Brittany from February 2010 the 17th to August 2015 the 30th, in adults over 20 years old. The investigators are aimed at studying physicians' use and eventually misuse of biomarkers dosage and the characteristics of a broad population based on some biomarkers concentrations.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
585,745

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2010

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 17, 2010

Completed
5.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 30, 2015

Completed
11 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 10, 2015

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

August 16, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 18, 2017

Completed
Last Updated

August 22, 2017

Status Verified

August 1, 2017

Enrollment Period

5.5 years

First QC Date

August 16, 2017

Last Update Submit

August 18, 2017

Conditions

Biological MarkersInappropriate Prescribing

Keywords

Biological markersProfessional practiceBig data analysisMeasured concentrationsCardiac markersTroponinNTproBNPCreatininINRHemogramLipid profile

Outcome Measures

Primary Outcomes (1)

  • biomarker dosage prescription

    physicians' use and eventually misuse of biomarkers dosage

    August 2017

Secondary Outcomes (3)

  • Biomarkers dosage numbers

    August 2017

  • Biomarkers in geriatric patients

    August 2017

  • Population's characteristics

    August 2017

Interventions

Measured concentrations of biomarkersDIAGNOSTIC_TEST

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Cohort that included all analyses performed in a large subset of laboratories located in the French Brittany from February 2010 the 17th to August 2015 the 30th. The extract data corresponded to 74,502,510 analyses performed in 585,745 distinct adult patients \>20y

You may qualify if:

  • All adult patients \>20 that came to a participating lab (Biorance Laboratoires Réunis) during the study period for biological measurement

You may not qualify if:

  • DNA analysis, HIV test

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Avicenne Hospital

Bobigny, 93000, France

Location

Study Officials

  • Christophe Meune, MD PhD

    Avicenne Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

August 16, 2017

First Posted

August 18, 2017

Study Start

February 17, 2010

Primary Completion

August 30, 2015

Study Completion

September 10, 2015

Last Updated

August 22, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will not share

Only aggregated data are available

Locations

FR(1)