Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)
1 other identifier
observational
173,229
0 countries
N/A
Brief Summary
To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health professionals.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2017
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2017
CompletedFirst Submitted
Initial submission to the registry
August 11, 2017
CompletedFirst Posted
Study publicly available on registry
August 18, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2018
CompletedJuly 15, 2020
July 1, 2020
1.3 years
August 11, 2017
July 13, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Multiple skin diseases
Includes skin cancer, psoriasis, and other inflammatory and autoimmune skin diseases.
Skin disease/cancer [ NHS: Time Frame: 1984 - 2010 ] [ HPFS: Time Frame: 1986 - 2010 ]. Person time contribution from date of return of questionnaire to date of first report of skin disease/death/end of follow-up (whichever came first)
Study Arms (2)
Nurses' Health Study
See "Detailed Description"
Health Professionals Follow-Up Study
See "Detailed Description"
Interventions
Dietary nutrient intake (such as folate) and supplemental nutrient intake (such as folic acid)
Eligibility Criteria
See "Detailed Description"
You may qualify if:
- Participants of these two cohorts
You may not qualify if:
- Participants with missing data on dietary intake at baseline
- Participants with a prior history of cancer (except non-melanoma skin cancer)
- For skin cancer, non-white participants because of low risk of skin cancer (such as melanoma) and small numbers.
- For melanoma, participants with in-situ melanomas, which comprise tumours restricted to the epidermis of the skin.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Harvard School of Public Health (HSPH)lead
- National Institutes of Health (NIH)collaborator
- Brown Universitycollaborator
Related Publications (1)
Li WQ, Cho E, Weinstock MA, Mashfiq H, Qureshi AA. Epidemiological Assessments of Skin Outcomes in the Nurses' Health Studies. Am J Public Health. 2016 Sep;106(9):1677-83. doi: 10.2105/AJPH.2016.303315. Epub 2016 Jul 26.
PMID: 27459457RESULT
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 30 Years
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research Associate
Study Record Dates
First Submitted
August 11, 2017
First Posted
August 18, 2017
Study Start
January 1, 2017
Primary Completion
May 1, 2018
Study Completion
May 1, 2018
Last Updated
July 15, 2020
Record last verified: 2020-07