the Effects of Cerebral Collateral Circulation on the Outcome of Leukoaraiosis in High-risk Population
Prospective, Single Center, Observational, Clinical Trial of the Effects of Cerebral Collateral Circulation on the Outcome of Leukoaraiosis in High-risk Population
1 other identifier
observational
1,037
1 country
1
Brief Summary
This study observed the relationship between cerebral collateral circulation and the prognosis of leukoaraiosis in high-risk population. Cerebral collateral circulation and leukoaraiosis levels will be evaluated and followed up by magnetic resonance examination. The participants' clinical performance caused by leukoaraiosis will be assessed by a series of scales.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2017
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 3, 2017
CompletedFirst Posted
Study publicly available on registry
August 11, 2017
CompletedStudy Start
First participant enrolled
October 11, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2020
CompletedJuly 7, 2020
July 1, 2020
3.2 years
August 3, 2017
July 1, 2020
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
change in cognitive assessment scale score
It will be assessed by the Mini-Mental state examination (MMSE) and Montreal cognitive assessment (MoCA). Each assessment is scored 0-30, yielding a total between 0-60.
baseline and one year
Secondary Outcomes (3)
change in mood assessment Scale score
baseline and one year
change in gait evaluation score
baseline and one year
stroke
baseline and one year
Eligibility Criteria
Inpatients of physical exmination department or out-patients of neurology department in Zhongshan hospital Fudan University.
You may qualify if:
- Physical Examinees or out-patients
- The MRI scale score ≥ 2
You may not qualify if:
- History of stroke
- History of malignant tumor
- History of connective tissue disease
- Pregnant, trying to become pregnant or within 6 weeks after delivery
- serious infections
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
neurology department of Zhongshan hospital, Fudan University
Shanghai, Shanghai Municipality, 200032, China
Biospecimen
blood sample fingernail sample hair sample urinary sample
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Xin Wang
neurology department of Zhongshan hospital, Fudan University
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Year
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 3, 2017
First Posted
August 11, 2017
Study Start
October 11, 2017
Primary Completion
December 30, 2020
Study Completion
December 30, 2020
Last Updated
July 7, 2020
Record last verified: 2020-07
Data Sharing
- IPD Sharing
- Will not share